Non-Positive Pressure Ventilation in Hypoxemic Patients

Acute Respiratory Failure Clinical Trial

Official title: Non-Positive Pressure Ventilation in Hypoxemic Patients. A Randomized Study

Status Completed

Clinical Trial Summary

The study is aimed to assess the possible benefit of non-positive pressure mechanical support in front of conventional ventilation in patients admitted to the intensive care unit (ICU) because of pure hypoxemic respiratory failure.

Clinical Trial Description

Pure hypoxemic patients admitted to intensive care unit in a teaching hospital have been randomized to be treated by conventional ventilatory support or non-positive mechanical ventilation support. Those patients who did not benefit from the experimental non-positive ventilatory support, were intubated and conventionally mechanically ventilated and discarded for analysis. The primary outcome was mortality rate in both groups, and secondary outcomes were length of stay, improvement of oxygenation, and reduced complications rates. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Acute Respiratory Failure
• Respiratory Distress Syndrome, Adult
• Respiratory Insufficiency

• NCT number: NCT00925860
• Study type: Interventional
• Source: Hospital Provincial de Castellon
• Status: Completed
• Phase: Phase 4
• Start date: June 2001
• Completion date: June 2007