Timing of Target Enteral Feeding in the Mechanically Ventilated Patient

Status Completed

Clinical Trial Summary

This study tests the hypothesis that initial trophic enteral feedings will increase the time alive and free of mechanical ventilation as compared to initial goal enteral feedings in patients who are mechanically ventilated.

Clinical Trial Description

Mechanically ventilated patients, within 48 hours of initiating mechanical ventilation, are randomized in a 1:1 fashion to receive trophic enteral feedings for 96 hours followed by advancement to goal feeding rates or initial advancement to goal feeding rates. Primary endpoints are ventilator free days, ICU-free days, gastrointestinal intolerances, development of nosocomial infections, and mortality. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Acute Respiratory Failure
Respiratory Distress Syndrome, Adult
Respiratory Insufficiency

Clinical Trial Details

NCT number	NCT00252616
Study type	Interventional
Source	Vanderbilt University
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	September 2003
Completion date	October 2009

View Details

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