Clinical Spectrum and Outcome of Poisoning in Children Admitted to the Pediatric Emergency and Intensive Care Units at Sohag University Hospital

Acute Poisoning Clinical Trial

Official title:

Clinical Spectrum and Outcome of Poisoning in Children Admitted to the Pediatric Emergency and Intensive Care Units at Sohag University Hospital

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06447584
• Other study ID #: Soh-Med-24-5-2024-09MS
• Status: Recruiting
• Start date: June 1, 2024
• Est. completion date: June 1, 2025

Study information

• Verified date: June 2024
• Source: Sohag University
• Contact: Asmaa A Saber, resident
• Phone: 01115205714
• Email: asmaa_asaad_post[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Acute poisoning is a major health problem that leads to emergent hospital admission.It has become the main factor that harms children and leads to disability and death of children. Also, it is still a serious issue in developing countries where it represents a common cause of emergency department presentation and admission. Acute poisoning can be divided into two categories (accidental and intentional),accidental poisoning is common in children under five years, whereas intentional poisoning is more common in adolescents, WHO estimated that, in 2016, accidental poisoning caused 106,683 deaths and the loss of 6.3 million years of healthy life.

A study in Romania showed that intentional poisoning is the most common cause of poisoning among teenagers. Females are more vulnerable to suicidal or intentional poisoning than males. Medications, alcohol, and substance abuse are common poisoning agents among teenagers , another study at tertiary Indian hospital, pesticides, pharmaceutical drugs, and household products were the most common types of acute poisoning. Pesticides were reported as a cause of intentional and accidental poisoning. In agricultural areas, people were poisoned accidentally by pesticides that may be used for suicidal attempts because of their availability. Pharmaceutical drugs are also used for intentional poisoning due to the availability of street drugs and over-the-counter medications. Accidental poisoning by household products were observed in children and the most common products are hydrocarbon and naphthalene In Egypt acute poisoning represents a significant proportion of emergency visits of children and young people. This labors a burden on healthcare, society and economy and thus, it drain-s resources and multiplies workload . In fact, it is a preventable cause of morbidity and mortality. Children poisoning is a result of multiple risk factors including social, demographic, and industrial factors. Insufficient public awareness, easy accessibility to poison, negligence of caregivers, technological and industrial advances and even the nature of the environment are of the main causes.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: June 1, 2025
• Est. primary completion date: June 1, 2025
• Gender: All
• Age group: 1 Month to 18 Years

Eligibility

Inclusion Criteria:

• All patients admitted to pediatric emergency and intensive care units with claim or suspected to have acute poisoning aged from 1 month Up to 18 years old.

Exclusion Criteria:

• Children with chronic poisoning

• no clear history or clinical picture of definite toxic poison

• incomplete clinical data

Related Conditions & MeSH terms

• Acute Poisoning
• Emergencies
• Poisoning

Locations

Country	Name	City	State
Egypt	Sohag university Hospital	Sohag

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Abdel Baseer KA, Gad EF, Abdel Raheem YF. Clinical profile and outcome of acute organophosphate poisoning in children of Upper Egypt: a cross-sectional study. BMC Pediatr. 2021 Feb 26;21(1):98. doi: 10.1186/s12887-021-02563-w. — View Citation

Ballesteros MF, Williams DD, Mack KA, Simon TR, Sleet DA. The Epidemiology of Unintentional and Violence-Related Injury Morbidity and Mortality among Children and Adolescents in the United States. Int J Environ Res Public Health. 2018 Mar 28;15(4):616. doi: 10.3390/ijerph15040616. — View Citation

Heron M. Deaths: Leading Causes for 2015. Natl Vital Stat Rep. 2017 Nov;66(5):1-76. — View Citation

Jesslin J, Adepu R, Churi S. Assessment of prevalence and mortality incidences due to poisoning in a South Indian tertiary care teaching hospital. Indian J Pharm Sci. 2010 Sep;72(5):587-91. doi: 10.4103/0250-474X.78525. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Recovery Time of acute poisoning	Full Recovery with appropriate and timely medical intervention	1 year