Clinical Efficacy of Indomethacin in Early Treatment of Acute Pancreatitis

Status Recruiting

Clinical Trial Summary

Acute pancreatitis is a common critical disease of the digestive system. Accumulated data showed that overexpression of cyclooxygenase-2 (COX-2) in acute pancreatitis and experimental pancreatitis could be attenuated with COX-2 inhibitors. In recent years, it has been found that timely administration of indomethacin or diclofenac sodium to anus after ERCP can significantly reduce the incidence of AP after ERCP in patients at high risk of AP. The aim of this study was to evaluate the efficacy of rectal indomethacin in reducing the systemic inflammatory response syndrome (SIRS) score in AP patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Acute Pancreatitis
Pancreatitis
Systemic Inflammatory Response Syndrome

Clinical Trial Details

NCT number	NCT05637281
Study type	Interventional
Source	Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact	Yuahua Han
Phone	+86 0571 89713734
Email	hanyaohua@zju.edu.cn
Status	Recruiting
Phase	N/A
Start date	December 11, 2022
Completion date	December 11, 2023

View Details

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