Dachaihu Decoction Compound and Rhubarb Single Medicine in the Treatment of Acute Pancreatitis

Acute Pancreatitis Clinical Trial

Official title:

Comparison of Clinical Efficacy of Dachaihu Decoction Compound and Rhubarb Single Medicine in the Treatment of Acute Pancreatitis

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04990336
• Other study ID #: ZDWY.XHNK.003
• Status: Not yet recruiting
• Phase: N/A
• Start date: September 1, 2023
• Est. completion date: July 31, 2029

Study information

• Verified date: July 2021
• Source: Fifth Affiliated Hospital, Sun Yat-Sen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A large number of clinical studies have shown that oral administration, external application or enema of Chinese medicine can promote the recovery of gastrointestinal function and the absorption of pancreatic inflammation. The aims of the study is to explore the application of Dachaihu Decoction Compound (DDC)and Rhubarb Single Medicine (RSM) in the Treatment of Acute Pancreatitis.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 306
• Est. completion date: July 31, 2029
• Est. primary completion date: January 31, 2029
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Age from 18 to 65 years old

• Meet the diagnostic criteria of western medicine for acute pancreatitis, within 48 hours of onset

• Consent of the subjects, who sign the informed consent form

Exclusion Criteria:

• Women who are pregnant or breastfeeding

• Acute abdomen such as organic intestinal obstruction, gastrointestinal perforation, purulent cholangitis, etc.

• Patients with a history of severe heart, liver, kidney and other important organ diseases

• Patients with mental illness and malignant tumors

• People who have allergies, or are allergic to a certain drug ingredient

Related Conditions & MeSH terms

• Acute Pancreatitis
• Pancreatitis

Intervention

Combination Product:
• Dachaihu decoction compound
Dachaihu decoction compound includes Bupleurum, Rhubarb, Citrus aurantium, Scutellaria, Pinellia, White Peony, Jujube, Ginger.

Drug:
• Rhubarb single medicine
Rhubarb single medicine

Combination Product:
• Regular therapies
Regular therapies, such as fluid therapy, for acute pancreatitis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Fifth Affiliated Hospital, Sun Yat-Sen University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Significant and effective rate	Significant and effective rate after 7 days of treatment	7 days