Acute Pancreatitis Clinical Trial
Official title:
Body Parameters as an Independent Predictor of Acute Pancreatitis: A Propensity Score-matched Case-control Study
This study is to assess the predictive significance of visceral adipose tissue (VAT) and visceral adipose tissue /skeletal muscle tissue ratio (VAT/SMT ratio) for the prognosis in acute pancreatitis (AP) patients.
Acute pancreatitis (AP) is a sudden inflammation of the pancreas. However, one-fifth of
patients may develop severe complications with a mortality between 10%-20% It remains a
difficulty to find an effective method for prediction of severity of AP at early stage.
It is well-established that obesity (defined as body mass index[BMI]>30kg/m2 by the World
Health Organization) is a risk factor for AP and increases the incidence of systemic
complication, motality. There are a lot of parameters related to saropenic obesity, including
areas of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), skeletal muscle
tissue (SMT), and VAT/SMT ratio. it is unclear which parameter is the best predictor of
severe AP. Thus, this study is aimed to investigate the association between these parameters
and AP severity and find the best predictor of AP.
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