Effect of Early Mechanical Ventilation to Severe Acute Pancreatitis

Status Recruiting

Clinical Trial Summary

Acute lung injury (ALI) and acute respiratory distress syndrome(ARDS) represent the most common and earliest organ dysfunction in acute pancreatitis, presenting as dyspnea and intractable hypoxemia, with secondary bilateral pulmonary infiltrates on radiograph. And mechanical ventilation (MV) is the essential intervention to improve oxygenation. When to initiate MV remains uncertain. In this study, we aim to compare the effect of early MV and conventional MV, and we hypothesize that early MV may be a better treatment option.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Acute Pancreatitis
Complication of Ventilation Therapy
Pancreatitis

Clinical Trial Details

NCT number	NCT01992224
Study type	Interventional
Source	Ruijin Hospital
Contact	Erzhen CHEN, MD
Phone	86-13901753478
Email	chenerzhen@hotmail.com
Status	Recruiting
Phase	N/A
Start date	July 2012
Completion date	June 2016

View Details

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