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Oral Refeeding IntOlerance After Nasogastric Tube Feeding (ORION) — ORION  

Acute Pancreatitis Clinical Trial

Official title:
A Randomized Controlled Trial of Oral Refeeding Intolerance After Nasogastric Tube Feeding

Clinical Trial Summary

Acute pancreatitis (AP) is one of the most common diseases in routine clinical practice of surgeons and gastroenterologists throughout the world. The high rate of pain relapse after oral refeeding contributes to high consumption of healthcare resources and prolonged hospital stay in AP patients. The data from the pilot MIMOSA trial suggest that early administration of nasogastric tube feeding may prevent pain relapse after oral refeeding in AP. The potential beneficial effects of enteral tube feeding include induction of postprandial gastrointestinal motility and improving the tolerance of oral refeeding. This may reduce the risk of pain relapse, thereby shortening length of hospital stay and reducing cost of treatment. The primary endpoint of the ORION trial will be the incidence of oral food intolerance. All eligible AP patients will be randomly allocated to either the Early Nasogastric Tube (ENT) group or Conventional Nutritional Management group (CNM) at 24h of hospital admission.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01798511
Study type Interventional
Source University of Auckland, New Zealand
Contact
Status Withdrawn
Phase N/A
Start date April 1, 2013
Completion date April 1, 2020
View Details
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