Ketamine Infusion for Sickle Cell Pain Crisis

Status Withdrawn

Clinical Trial Summary

The purpose of this study is to prospectively study the efficacy of low dose ketamine infusions in treating patients who are admitted to the hospital with a sickle cell pain crisis. Participants will be prospectively randomized in unblinded fashion in the first 12 to 24 hours of an inpatient admission for sickle cell pain crisis to receive pain management without ketamine infusion (Group A) versus pain management that includes low-dose ketamine infusion starting at 0.2mg/kg/h (Group B). The effect of this intervention on various pain management and healthcare utilization outcome measures will be recorded and analyzed to determine whether or not there is a measurable benefit of using ketamine infusions in this patient population.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04005209
Study type	Interventional
Source	Duke University
Contact
Status	Withdrawn
Phase	Phase 4
Start date	January 2022
Completion date	November 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04484610` - Appropriate Opioid Quantities for Acute Pain - Pharmacist Study	Phase 4
Recruiting	`NCT05054179` - Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain	Phase 2/Phase 3
Completed	`NCT04548635` - VR for Burn Dressing Changes at Home	Phase 2/Phase 3
Recruiting	`NCT05370404` - Prescribing vs. Recommending Over-The-Counter (PROTECT) Analgesics for Patients With Postoperative Pain:	N/A
Completed	`NCT06054945` - Clinical Impact of IPACK Block Addition to Suprainguinal Fascia Iliaca Block
Completed	`NCT03825549` - A Randomized Trial of Behavioral Economic Approaches to Reduce Unnecessary Opioid Prescribing	N/A
Completed	`NCT05995912` - Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain	Phase 2
Recruiting	`NCT05589246` - Regional Analgesia in Combination With Cryoanalgesia to Prevent Acute Pain Following Nuss Procedure	N/A
Recruiting	`NCT05572190` - Evaluate the Safety and Pharmacokinetic Profile of ETR028 and ETR029 in Healthy Adult Subjects	Phase 1
Terminated	`NCT04716413` - Evaluating the Use of Sublingual Sufentanil in Patients With Suboxone Treatment	Phase 4
Active, not recruiting	`NCT03537573` - Provider-Targeted Behavioral Interventions to Prevent Unsafe Opioid Prescribing for Acute Pain in Primary Care	N/A
Not yet recruiting	`NCT06317844` - Examination of Psychological and Physiological Pathways Linking Gratitude and Pain	N/A
Withdrawn	`NCT02957097` - Gabapentin as a Pre-emptive Analgesic in Oral and Maxillofacial Surgical Procedures	Phase 4
Completed	`NCT02565342` - Interscalene Brachial Plexus Block to Treat Pain After Clavicular Surgery	Phase 4
Terminated	`NCT02599870` - Clinical Study to Evaluate Clinical Impact of PGx-Guided Treatment for Patients Undergoing Elective Spinal Surgical Procedures	N/A
Completed	`NCT02984098` - 40% Orally Administered Dextrose Gel is More Effective Than 25% Dextrose	Phase 4
Completed	`NCT02380989` - Integrative Ayurveda Healing Relieves Minor Sports Injury Pain	Phase 2
Completed	`NCT03107338` - Preventive Treatment of Pain After Dental Implant Surgery	Phase 4
Completed	`NCT02489630` - Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department	Phase 4
Completed	`NCT02817477` - Intranasal Ketamine for Acute Traumatic Pain	Phase 4