Acute Pain Clinical Trial
Official title:
Comparison of IV Paracetamol With Intravenous Morphine Sulfate in Treatment of Acute Pain Due to Limb Trauma
The purpose of this study is to determine whether Iv paracetamol is as effective as Iv Morphine sulfate on control of the acute pain in Patient with limb trauma.
Status | Completed |
Enrollment | 60 |
Est. completion date | December 2012 |
Est. primary completion date | September 2012 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Clinical diagnosis of acute limb trauma - Age>=18 years - Acute pain of score 3 or greater on visual analogue scale Exclusion Criteria: - Unstable hemodynamic (Systolic blood pressure under 90 mmHg) - Known sensitivity to opioids or paracetamol - Any other known contraindication to Morphine Sulfate or Iv Paracetamol (including severe allergy to these drugs, acute bronchial asthma, upper respiratory tract obstruction) - Previous administration of analgesic during 6 hours ago - Pregnant women - previous inclusion to the study - diagnosed heart failure - renal failure - pulmonary failure or hepatic failure |
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Iran, Islamic Republic of | TUMS | Tehran |
Lead Sponsor | Collaborator |
---|---|
Tehran University of Medical Sciences |
Iran, Islamic Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in pain severity/score | after 30 minutes | No | |
Secondary | Need for rescue analgesia | After 30 minutes | Yes |
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