Acute Lung Injury Clinical Trial
Official title:
Assessment of Patient-ventilator Asynchrony by Electric Impedance Tomography and Artificial Intelligence
Patient-ventilator asynchrony (PVA) has deleterious effects on the lungs. PVA can lead to acute lung injury and worsening hypoxemia through biotrauma. Little is known about how PVA affects lung aeration estimated by electric impedance tomography (EIT). Artificial intelligence can promote the detection of PVA and with its help, EIT measurements can be correlated to asynchrony.
Patient-ventilator asynchrony (PVA) is a common phenomenon with invasively- and non-invasively ventilated patients. PVA has deleterious effects on the lungs. It causes not just patient discomfort and distress but also leads to acute lung injury and worsening hypoxemia through biotrauma. The latter significantly impacts outcomes and increases the duration of mechanical ventilation and intensive care unit stay. However, PVA is a widely investigated incident related to mechanical ventilation, though little is known about how it affects lung aeration estimated by electric impedance tomography (EIT). EIT is a non-invasive, real-time monitoring technique suitable for detecting changes in lung volumes during ventilation. Artificial intelligence can promote the detection of PVA by flow versus time assessment. If continuous EIT recording is correlated with the latter, impedance tomography changes evoked by asynchrony can be estimated ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03937947 -
Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
|
||
Completed |
NCT04247477 -
Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS
|
N/A | |
Completed |
NCT03315702 -
Effect of Mechanical Ventilation on Plasma Concentration Level of R-spondin Proteins
|
||
Not yet recruiting |
NCT02693912 -
Changes in Alveolar Macrophage Function During Acute Lung Injury
|
N/A | |
Completed |
NCT01659307 -
The Effect of Aspirin on REducing iNflammation in Human in Vivo Model of Acute Lung Injury
|
Phase 2 | |
Completed |
NCT01552070 -
Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS)
|
Phase 2 | |
Unknown status |
NCT01186874 -
Epidemiology Research on Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) in Adult ICU in Shanghai
|
N/A | |
Withdrawn |
NCT00961168 -
Work of Breathing and Mechanical Ventilation in Acute Lung Injury
|
N/A | |
Recruiting |
NCT00759590 -
Comparison of Two Methods to Estimate the Lung Recruitment
|
N/A | |
Completed |
NCT00736892 -
Incidence of Acute Lung Injury: The Alien Study
|
||
Completed |
NCT02475694 -
Acute Lung Injury After Cardiac Surgery: Pathogenesis
|
N/A | |
Completed |
NCT00825357 -
Biological Markers to Identify Early Sepsis and Acute Lung Injury
|
N/A | |
Terminated |
NCT00263146 -
Recruitment Maneuvers in ARDS: Effects on Respiratory Function and Inflammatory Markers.
|
N/A | |
Completed |
NCT00188058 -
Comparison of 2 Strategies of Adjustment of Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome
|
N/A | |
Completed |
NCT00234767 -
Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS)
|
Phase 3 | |
Recruiting |
NCT02598648 -
Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in Neonates
|
N/A | |
Recruiting |
NCT02948530 -
Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods (Lungbarometry)
|
||
Completed |
NCT01532024 -
Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs
|
Early Phase 1 | |
Recruiting |
NCT01992237 -
Measuring Energy Expenditure in ECMO (Extracorporeal Membrane Oxygenation) Patients
|
N/A | |
Completed |
NCT01486342 -
PET Imaging in Patients at Risk for Acute Lung Injury
|
N/A |