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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT00950508
Other study ID # EMPET-001
Secondary ID
Status Completed
Phase N/A
First received July 29, 2009
Last updated November 4, 2014
Start date June 1998
Est. completion date July 2009

Study information

Verified date November 2014
Source Rigshospitalet, Denmark
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The aim of this study is to examine if high-volume plasma exchange has a positive effect on mortality in patients with acute liver failure.


Recruitment information / eligibility

Status Completed
Enrollment 183
Est. completion date July 2009
Est. primary completion date July 2009
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- Patients with acute liver failure in encephalopathy grade 2-4

Exclusion Criteria:

- alcoholic hepatitis

- primary non function liver graft or graft dysfunction

- known chronic liver disease

- known malignancies

- clinical suspicion of brain death

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
High volume plasma exchange
3 high volume plasma exchanges over 3 days
Standard medical treatment
Standard medical treatment

Locations

Country Name City State
Denmark Department of Hepatology, Rigshospitalet Copenhagen DK
Finland Department of Transplantation and Liver Surgery, Helsinki University Hospital Helsinki
United Kingdom Institute of Liver Studies, King's College Hospital London

Sponsors (1)

Lead Sponsor Collaborator
Rigshospitalet, Denmark

Countries where clinical trial is conducted

Denmark,  Finland,  United Kingdom, 

Outcome

Type Measure Description Time frame Safety issue
Primary mortality at day 3, day 7
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