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NCT06005896 Clinical Trial

A Clinical Model for Dialysis Discontinuation in AKI

Acute Kidney Injury Clinical Trial

Official title:
A Clinical Model to Predict Successful Renal Replacement Therapy (RRT) Discontinuation in Patients With Acute Kidney Injury (AKI)

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06005896
Other study ID # 51678521.0.0000.0068
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 1, 2020
Est. completion date February 1, 2022

Study information
Verified date August 2023
Source University of Sao Paulo General Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

A retrospective study evaluating AKI patients in whom RRT was interrupted for at least 48 hours. Patients who were still RRT-independent 7 days after initial RRT cessation were included in the "Success" group, as opposed to the "Failure" group. Baseline characteristics and variables at the time of RRT interruption were collected. Multivariable analysis was performed and a model was generated to evaluate the prediction of success.

Recruitment information / eligibility
Status Completed
Enrollment 124
Est. completion date February 1, 2022
Est. primary completion date February 1, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - All patients receiving kidney replacement therapy due to AKI from October 2020 to February 2022 were considered for inclusion in the study. Patients who managed to remain at least 48 consecutive hours without receiving kidney replacement therapy prescription were included. Exclusion Criteria: - Patients who had kidney replacement therapy interrupted exclusively due to haemodynamic instability, death or decision for palliative care were excluded.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Brazil University of São Paulo School of Medicine São Paulo SP

Sponsors (1)
Lead Sponsor Collaborator
University of Sao Paulo General Hospital

Country where clinical trial is conducted

Brazil, 

Outcome
Type Measure Description Time frame Safety issue
Primary Success in RRT discontinuation To be alive and free from RRT 7 days after interrupting RRT. 7 days
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