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Role of Neuronal Guidance Proteins as Diagnostic Markers for Acute Kidney Injury (AKI) — NEUKID  

Acute Kidney Injury Clinical Trial

Official title:
Role of Neuronal Guidance Proteins as Diagnostic Markers for Acute Kidney Injury (AKI)

Clinical Trial Summary

Acute kidney failure remains one of the most challenging entities to diagnose in clinical medicine, especially in the field of intensive care. The diagnosis of acute kidney injury is based solely on urine output and serum creatinine, both of which could also be influenced by other factors. A more sensitive and faster diagnostic option would not only be desirable but of utmost clinical importance. Therefore, the investigators aim to identify Neuronal Guidance Proteins (NGPs) as potential biomarkers for the identification and early detection of AKI with this investigation. This investigation aims to identify the possibility of diagnosing acute kidney injury, the subsequent validation of a potential biomarker will then have to take place in a multicenter study approach: Data in preclinical mouse models suggest that SEMA7A as one of the NGPs could be valuable as a biomarker, the study now aims to attempt a preliminary survey in humans and measure various NGPs.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05924269
Study type Observational
Source University Hospital Tuebingen
Contact Andreas Körner, MD
Phone +497071-29 61783
Email andreas.koerner@med.uni-tuebingen.de
Status Not yet recruiting
Phase
Start date August 2023
Completion date July 2026
View Details
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