Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT05381493 |
| Other study ID # |
AnkaraUTraumaAKI |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
January 1, 2021 |
| Est. completion date |
May 10, 2022 |
Study information
| Verified date |
May 2022 |
| Source |
Ankara University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
Acute kidney injury (AKI) is a common complication that increases lenght of stay and
mortality in trauma patients admitted to the intensive care unit (ICU). The aim of this study
is to identify the incidence and outcomes of trauma patients, defined by Kidney Disease
Improving Global Outcomes (KDIGO) criteria, at single center level 3 ICU.
Description:
Trauma can cause high mortality and morbidity by affecting different organ systems. Acute
kidney injury (AKI) is a common complication in trauma patients admitted to the intensive
care unit (ICU). Direct kidney injury, hypotension, hypoperfusion, rhabdomyolysis, abdominal
compartment syndrome, sepsis and critical care medications are possible causes of AKI in
trauma patients. The incidence of AKI can be up to 10%, and mortality rate up to 60-80% in
trauma patients. Since AKI is not only a rare complication but also a risk factor for
mortality in critically ill trauma patients, it is essential to establish a strategy to
prevent AKI and related complications, to determine the incidence and risk factors of AKI,
and to improve patients outcomes. Survivors of AKI may have variable recovery of kidney
function and might prone to late morbidity and mortality. In this study incidence of AKI was
defined using the KDIGO criteria according to the change of serum creatine levels.
171 all type of trauma patients admitted to level 3 ICU, from January 2014 to December 2018
included the retrospectve observational study. Demographic data, type of injury, rates of
complications, risk factors for AKI, mortality, lenght of stay (LOS) in ICU were evaluated.
Acute Physiology and Chronic Health Evaluation (APACHE II and IV) score, Simplified Acute
Physiology Score (SAPS II and III), Glasgow Coma Scale (GCS), Injury Severity Score (ISS)
and, Trauma Injury Severity Score (TRISS) were calculated on the day of admission. AKI was
defined using the KDIGO criteria according to the serum creatinine. The SPSS 11.5 program was
used for statistical analysis.
