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The Effect of Fluid Management by Pleth Variability Index on Acute Kidney Injury in Obese Patients

Acute Kidney Injury Clinical Trial

Official title:
The Effect of Fluid Management by Pleth Variability Index on Acute Kidney Injury in Obese

Clinical Trial Summary

This study was to find out whether laparoscopic colorectal surgery is detrimental to the kidneys via PVI monitoring. To detect the kidney injury, so-called kidney troponin NGAL ,which gives earlier information than creatin in renal ischemic injury, was used.

Clinical Trial Description

Our object in this study was to find out whether laparoscopic colorectal surgery is detrimental to the kidneys via PVI monitoring. To detect the kidney injury, so-called kidney troponin NGAL ,which gives earlier information than creatine in renal ischemic injury, was used.

Patients undergoing elective laparoscopic colorectal surgery, 18 to 75 years old, planned surgery duration longer than 2 hours, were included in this study. Patients were divided into 2 groups with respect to their fluid resuscitation, Group 1: goal directed fluid therapy via PVI monitoring Group 2: conventional fluid resuscitation. Blood samples were drawn from both groups for NGAL measurement before CO2 insufflation (T0), and at 6th(T1) and 12th(T2) hours after CO2 insufflation. At the end of the surgery, sugammadex was given to all patients for reversal of muscular blockade. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03408834
Study type Interventional
Source Ankara University
Contact
Status Completed
Phase N/A
Start date January 2, 2016
Completion date October 2, 2017
View Details
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