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Renal Effects of RIPC in Patients After Total Arch Replacement — RenRIPC-TAR  

Acute Kidney Injury Clinical Trial

Official title:
Renal Effects of Remote Ischemic Preconditioning in Patients After Total Arch Replacement

Clinical Trial Summary

The purpose of this study is to test the hypothesis that remote ischemic preconditioning prevents acute kidney injury and improves clinical outcomes in patients undergoing total arch replacement.

Clinical Trial Description

Acute kidney injury (AKI) is a well-recognized complication after cardio-thoracic surgeries and is associated with increased morbidity and mortality. Total arch replacement is reported with a relatively high incidence of post-operative AKI. In addition, few effective preventive or therapeutic interventions for AKI have been identified. A number of studies have now addressed renal protection as a primary outcome following RIPC. Because the mechanism of I/R injury are similar to those proposed for AKI after CPB, the purpose of this study is to test the hypothesis that remote ischemic preconditioning prevents acute kidney injury and improves clinical outcomes in patients undergoing total arch replacement. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03141385
Study type Interventional
Source Chinese Academy of Medical Sciences, Fuwai Hospital
Contact
Status Completed
Phase N/A
Start date April 7, 2017
Completion date May 30, 2018
View Details
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