China Collaborative Study on Epidemiology of Acute Kidney Injury

Acute Kidney Injury Clinical Trial

Official title:

China Collaborative Study on Epidemiology of Acute Kidney Injury

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03054142
• Other study ID #: CCS-AKI RF2011-2016
• Status: Recruiting
• Start date: January 2017
• Est. completion date: December 31, 2027

Study information

• Verified date: December 2022
• Source: Guangdong Provincial People's Hospital
• Contact: Liang Xinling, M.D.,Ph.D
• Phone: 13808819770
• Email: xinlingliang[@]139.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Acute kidney injury (AKI) is a common clinical syndrome, especially patients in the hospital. AKI has become a huge medical burden in China. Little information is available about this disease burden in our country. The investigators aimed to evaluate the burden of AKI and to analyze the related risk factors.

Description:

The investigators launch a nationwide of all patients, who were admitted to hospital from 2011-2016. Patients were diagnosed on the basis of changes in serum creatinine by the laboratory information system. The investigators assessed rates of AKI according to the criteria of 2012 Kidney Disease Improving Global Outcomes (KDIGO).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1000000
• Est. completion date: December 31, 2027
• Est. primary completion date: December 31, 2027
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• The patients diagnosed on the basis of changes in serum creatinine according to the criteria of 2012 Kidney Disease Improving Global Outcomes(KDIGO)

Exclusion Criteria:

• Serum creatinine record less than two times during hospitalization
• Patients being diagnosed with End-stage kidney disease (chronic kidney disease stage 5)
• Nephrectomy
• Kidney transplantation
• Peak serum creatinine of less than 53µ mol/L
• Serum creatinine decrease after amputation

Related Conditions & MeSH terms

• Acute Kidney Injury
• Wounds and Injuries

Intervention

Other:
• no intervention

Locations

Country	Name	City	State
China	Nephrology Dept,Guangdong General Hospital	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
XinLing Liang

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of AKI		Jan. 2011 to Oct. 2016
Secondary	Recognition rate of AKI	Using machine learning and deep learning methods to establish AKI prediction model and risk models	Jan. 2011 to Oct. 2016
Secondary	Proportion of nephrology referral		Jan. 2011 to Oct. 2016
Secondary	In-hospital mortality		Jan. 2011 to Oct. 2016
Secondary	Longer ICU stay		Jan. 2011 to Oct. 2016
Secondary	Higher medical cost		Jan. 2011 to Oct. 2016