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Preventing Contrast-induced Nephropathy: Evaluating Hydration Strategies and L-carnitine Administration — CinBiCarn  

Acute Kidney Injury Clinical Trial

Official title:
Preventing Nephropathy Induced by Iodinated Contrast Media in Patients With Renal Impairment: a Randomized Trial Evaluating the Effectiveness of Two Hydration Strategies and L-carnitine Administration

Clinical Trial Summary

The general objective of this open, pilot study is to characterize biological parameters related to acute kidney injury among patients undergoing a programmed coronarography with injection of contrast material. The study focuses on two main factors that may influence acute kidney injury: (1) sodium chloride hydration strategy versus sodium bicarbonate hydration strategy and (2) presence of oral L-carnitine treatment versus absence of oral L-carnitine treatment. We will also test for a potential interaction between these two factors.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01786824
Study type Interventional
Source Centre Hospitalier Universitaire de Nimes
Contact
Status Terminated
Phase Phase 3
Start date December 2014
Completion date August 2015
View Details
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