Acute Kidney Failure Clinical Trial
Official title:
Ioxaglate Versus Iodixanol for the Prevention of Contrast-induced Nephropathy in High-risk Patients After Diagnostic and Therapeutic Cardiac Catheterization (IDPC Trial)
Contrast media-induced nephropathy following diagnostic and therapeutic cardiac catheterization.
Contrast-induced acute kidney injury represents a serious complication of procedures
requiring administration of iodinated contrast media and is associated with the need for
dialysis, prolonged hospitalization, increased costs, and mortality.
Contrast-induced nephropathy is defined as an increase of 25% in serum creatinine before the
procedure.
Iodixanol, a nonionic, dimeric, iso-osmolar contrast medium may be less nephrotoxic than
low-osmolar contrast media in high-risk patients.
The purpose of this study is to compare iodixanol versus ioxaglate in high risk patients
between 48 and 96 hours after procedures that use contrast.
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Observational Model: Cohort, Time Perspective: Prospective
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