Acute Kidney Failure Clinical Trial
Official title:
Change of Neutrophil Gelatinase-Associated Lipocalin(NGAL) Following Sodium Phosphate Bowel Preparation(Pilot Study)
Oral phosphate purgative is the preferred bowel regimen on the basis of better tolerability, cost effectiveness, and efficacy. There are also numerous reports of patients with even previously normal renal function developing acute and chronic kidney disease after use of oral phosphate purgative. Several uncontrolled case reports and case series suggest a potential link between oral phosphate and acute kidney injury and/or chronic kidney disease1. Its use is contraindicated in patients with preexisting renal disease because of the risk for developing acute renal failure, so called acute phosphate nephropathy, or electrolyte disturbance. Since most of the outpatients who are going to undergo a colonoscopy are exposed to this agent, it is important to detect or prevent vulnerable patients. We would seek a sensitive and rapid diagnosis method of acute kidney injury following sodium phosphate bowel preparation. Within a few hours, NGAL mRNA is highly upregulated after kidney injury, such as renal ischemia-reperfusion and cisplatin nephropathy, NGAL induction precedes the elevation of classical markers for kidney damage such as serum creatinine. The investigators will investigate the change of NGAL following sodium phosphate bowel preparation.
n/a
Observational Model: Cohort, Time Perspective: Prospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00890214 -
Prostacyclin's Effect on Platelet Responsiveness
|
Phase 4 | |
Active, not recruiting |
NCT03675906 -
The Relationship Between Hypoalbuminemia and Development of Acute Kidney Failure (AKI) According to KDIGO Criteria
|
||
Recruiting |
NCT04334707 -
Kidney Precision Medicine Project
|
||
Active, not recruiting |
NCT04079829 -
Postoperative Respiratory Abnormalities
|
||
Recruiting |
NCT00424320 -
Clinical Trial of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy
|
Phase 3 | |
Completed |
NCT00472563 -
Prevention of Contrast Induced Nephropathy With Sodium Bicarbonate
|
Phase 2/Phase 3 | |
Withdrawn |
NCT03846258 -
High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy
|
Phase 4 | |
Completed |
NCT06358365 -
Enhancing Fluid Transfer Through the Skin, by Increased Sweat Rate, on Hemodialysis Patients
|
N/A | |
Completed |
NCT00252200 -
BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.
|
Phase 1/Phase 2 | |
Completed |
NCT04190979 -
Clinical Application of the Medyria TrackCath System in Endovascular Repair of Abdominal Aortic Aneurysms (AAA)
|
N/A | |
Completed |
NCT04917497 -
Levosimendan Infusion in Critically Ill Patients With Cardiogenic Shock
|
||
Recruiting |
NCT05309291 -
Theranova Randomized, Controlled, Trial (RCT) in China
|
N/A | |
Completed |
NCT02486614 -
Effect of Citrate on the Coagulation System in Patients Receiving CRRT
|
||
Active, not recruiting |
NCT02470507 -
Immune Function in Acute Kidney Injury
|
||
Active, not recruiting |
NCT05384899 -
Kidney Precision Medicine Project (KPMP) - COVID-19 Protocol
|
||
Completed |
NCT06190522 -
Diagnosis of Acute Obstructive Renal Failure by Clinical Ultrasound Performed by the Emergency Physician.
|
||
Recruiting |
NCT04221932 -
Implementation of CRRT KPI Reports to Standardize and Improve the Quality of CRRT Delivery in Alberta "QUALITY CRRT"
|
||
Active, not recruiting |
NCT01122225 -
Neutrophile Gelatinase Associated Lipocalin Evaluation in Septic Acute Kidney Injury
|
N/A | |
Completed |
NCT00529139 -
Hannover Dialysis Outcome Study
|
Phase 4 | |
Recruiting |
NCT04445779 -
Q10 Preloading Before Cardiac Surgery for Kidney Failure Reduction
|
N/A |