Acute Bronchiolitis Clinical Trial
Official title:
Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department
Verified date | January 2018 |
Source | Seoul National University Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This is a prospective, randomized, controlled, double-blinded, clinical trial
Subject : 3mo ~ 24mo. aged infants with bronchiolitis
The effect of 3 % NaCl nebulizer or dexamethasone on admission rate of these infants in ED.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 3 Months to 24 Months |
Eligibility |
Inclusion Criteria: - 3mo ~ 24mo aged patients with bronchiolitis visit to emergency departments - RDAI score 4-15 Exclusion Criteria: - < 3mo, > 24mo - infants who had received oral or inhaled corticosteroids during the preceding 2 weeks - infants with a previous episode of wheezing or a diagnosis of asthma - any chronic cardiopulmonary disease - immunodeficiency - infants needed intubation - infants with a previous history of apnea or intubation - infants with side effect of dexamethasone - infants born at less than 37 weeks of gestation who had a corrected age of less than 6 weeks at presentation |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Seoul National University Bundang Hospital | Seongnam-si | Gyeonggi-do |
Lead Sponsor | Collaborator |
---|---|
Seoul National University Hospital |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | hospital admission within 7 days after the day of enrollment | hospital admission within 7 days after the day of enrollment(the initial visit to the emergency department) | within 7 days | |
Secondary | RDAI score | RDAI score | baseline, between nebulizer, 60min, 120min, 180min, 240min | |
Secondary | respiratory rate | respiratory rate | baseline, between nebulizer, 60min, 120min, 180min, 240min | |
Secondary | Heart rate | Heart rate | baseline, between nebulizer, 60min, 120min, 180min, 240min | |
Secondary | Oxygen saturation | Oxygen saturation | baseline, between nebulizer, 60min, 120min, 180min, 240min | |
Secondary | unplanned revisit and admission rate after revisit | unplanned revisit admission rate after revisit | in 7days |
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