ANGH Prospective Cohort of Mild and Severe Acute Biliary Pancreatitis — CAPABLES  

Acute Biliary Pancreatitis Clinical Trial

Official title: ANGH Prospective Cohort of Mild and Severe Acute Biliary Pancreatitis

Status Not yet recruiting

Clinical Trial Summary

The main objective of this work is to evaluate the recurrence of biliary episodes before cholecystectomy (hepatic colic, lithiasic migration, cholangitis, cholecystitis, pancreatitis, necrosis infections) in patients with acute biliary pancreatitis of any severity depending on the type of nutrition (oral, enteral or parenteral).

Clinical Trial Description

Acute pancreatitis (AP) is one of the frequent causes of hospitalization in gastroenterology with an annual incidence of 13-45 cases per 100,000 patients. If we refer to the data in the white paper, hospitalizations for abdominal emergencies, such as PA, take place in at least 60% of cases in General Hospital Centers (CHG). Among these AP, approximately 40% of AP are secondary to a biliary lithiasis pathology. The main modalities of the initial management of AP have been the subject of several national and international recommendations and consensuses. Although it is well accepted that early refeeding during the first 48 hours reduces the appearance of a systemic inflammatory response syndrome (SIRS) or a collection infection, the feeding methods in the event of pancreatitis Acute biliary (ABP) during the acute phase using the oral route if it is tolerated or the enteral route by nasogastric tube before cholecystectomy remains debated.

Thus, in case of delayed cholecystectomy after AP, there is no consensus on the feeding methods after the acute phase (oral or enteral) until cholecystectomy nor on the benefit of a prophylactic endoscopic sphincterotomy in the absence of cholangitis. ;

Related Conditions & MeSH terms

• Acute Biliary Pancreatitis
• Pancreatitis

• NCT number: NCT05549349
• Study type: Observational [Patient Registry]
• Source: Poissy-Saint Germain Hospital
• Contact: Julia Travagli, phD
• Phone: +33 1 39 27 40 47
• Email: julia.gross@ght-yvelinesnord.fr
• Status: Not yet recruiting
• Start date: October 10, 2022
• Completion date: March 10, 2023