Acne Vulgaris Clinical Trial
Official title:
Comparative Study of Metformin Versus Doxycycline in Treatment of Moderate to Severe Adult Acne Vulgaris Patients: Multicentre, Randomized, Double-blind Trial.
The goal of this clinical trial is to compare the effect of doxycycline and metformin in treatment of acne vulgaris patients. The main question is aimed to answer is whether metformin is more effective than doxycycline in treatment of acne vulgaris patient or not. Patients will be asked to take doxycycline along with tropical treatment in one group and metformin along with tropical treatment in another group. Researcher will compare the clinical improvement in two groups.
| Status | Recruiting |
| Enrollment | 120 |
| Est. completion date | March 2024 |
| Est. primary completion date | March 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: Newly diagnosed moderate and severe AV patients diagnosed by a dermatologist - Exclusion Criteria: - Patients receiving topical retinoids within last two months - Pregnancy and lactation - History of corticosteroids intake - Suffering from malignancy or any cosmetic induced acne |
| Country | Name | City | State |
|---|---|---|---|
| Bangladesh | BSMMU | Dhaka |
| Lead Sponsor | Collaborator |
|---|---|
| Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
Bangladesh,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Global Acne Grading System (GAGS) Score | Acne Vulgaris Severity assesment by GAGS score | 12 weeks |
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|---|---|---|---|
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