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NCT04555018 Clinical Trial

Correlation Between Dehydroepiandrosterone Sulfate and Sebum Level in Adult Female Acne Vulgaris

Acne Vulgaris Clinical Trial

Official title:
Correlation Between Dehydroepiandrosterone Sulfate and Sebum Level in Adult Female Acne Vulgaris

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04555018
Other study ID # DheasSebum
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 1, 2017
Est. completion date October 1, 2017

Study information
Verified date September 2020
Source Indonesia University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. A cross sectional study was conducted with 50 samples, in June to October 2017.

Description:

Epidemiological studies have shown that number of adult female acne vulgaris (AV) increases. Hormone, sebum production, Propionibacterium acne and inflammatory process are factors involved in AV development. The aim of this study is to determine the correlation between Dehydroepiandrosterone sulfate (DHEAS) and sebum level in adult female acne. This research used cross sectional study with 50 samples, aged 25-49 years by consecutive sampling. The degree of acne vulgaris was evaluated using Lehman criteria , and then the sebum level and DHEAS were measured objectively using sebumeter and serum, respectively.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date October 1, 2017
Est. primary completion date September 1, 2017
Accepts healthy volunteers
Gender Female
Age group 25 Years to 49 Years
Eligibility Inclusion Criteria:

- Female, age 25-29 years

- Diagnosed with mild to severe acne vulgaris

- Agree to participate

Exclusion Criteria:

- History of taking antiandrogen drugs

- History of taking oral and topical antibiotics, using topical retinoid and BPO in the last 4 weeks

- History of taking oral isotretinoin in the last 6 months

- Pregnancy or breastfeeding

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Indonesia Indonesia dr. Cipto Mangunkusumo Hospital Jakarta Jakarta Pusat

Sponsors (1)
Lead Sponsor Collaborator
Dr.dr.Irma Bernadette, SpKK (K)

Country where clinical trial is conducted

Indonesia, 

Outcome
Type Measure Description Time frame Safety issue
Primary Sebum level Using sebumeter to evaluate the sebum level objectively One day
Primary Dehydroepiandrosterone sulfate Blood serum was used to evaluate Dehydroepiandrosterone sulfate level. One day
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