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Acne Vulgaris clinical trials

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NCT ID: NCT00446043 Completed - Acne Vulgaris Clinical Trials

Long-term Study of Efficacy/Safety of Adapalene/Benzoyl Peroxide Topical Gel in Acne Vulgaris Subjects

Start date: February 17, 2004
Phase: Phase 3
Study type: Interventional

This was a multi-center, open-label, non-comparative study that evaluated the long-term safety and efficacy profile of Adapalene/Benzoyl Peroxide Gel. Subjects were evaluated at Baseline, Weeks 1 and 2, and Months 1, 2, 4, 6, 8, 10, and 12. Safety was evaluated by spontaneous reports of Adverse Events (AEs), the Local Tolerability Assessment (Erythema, Scaling, Dryness, and Stinging/Burning), routine laboratory testing (hematology, blood chemistry, and urinalysis), and monitoring of suspected sensitizations. Efficacy was evaluated by analysis of Percent Change from Baseline in Inflammatory, Noninflammatory, and Total Lesion Counts, and by the Subject's Assessment of Acne.

NCT ID: NCT00441805 Withdrawn - Acne Vulgaris Clinical Trials

The Treatment of Acne Vulgaris With Radiofrequency Device

Start date: November 2006
Phase: N/A
Study type: Interventional

Radiofrequency emmitting device, normaly used for thermage treatments will be used on 22 mild to moderate acne patients faces. The aim of the study is to check whether RF heating of subcutaneous and dermis will improve acne in needed patients.

NCT ID: NCT00441415 Completed - Acne Vulgaris Clinical Trials

Efficacy and Safety of Fixed Combination Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in the Treatment of Acne Vulgaris

Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the non-inferior efficacy of Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel when compared to Clindamycin 1% / Benzoyl Peroxide 5% Gel in Subjects with acne vulgaris after a 12-week treatment period.

NCT ID: NCT00437151 Completed - Acne Clinical Trials

Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1%

Start date: June 2006
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to investigate potential differences in treatment adherence by teenagers among four interventions during treatment for acne.

NCT ID: NCT00422240 Completed - Acne Vulgaris Clinical Trials

Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris

Start date: June 27, 2006
Phase: Phase 3
Study type: Interventional

This was a multi-center, randomized, double-blind, parallel group study with 12 weeks of treatment of acne vulgaris. Efficacy and safety evaluations were performed at Screening (safety only), Baseline and Weeks 1, 2, 4, 8 and 12. All Investigator's Global Assessment evaluators and lesion counters must be trained and approved by Galderma. The evaluator of a participant should remain the same during the study. The primary objective was to demonstrate the superiority in efficacy and assess safety of adapalene/benzoyl peroxide topical gel (adapalene/benzoyl peroxide gel) versus adapalene topical gel, 0.1% (adapalene monad); benzoyl peroxide topical gel, 2.5% (benzoyl peroxide monad) and topical gel vehicle (gel vehicle) in the treatment of acne vulgaris for up to 12 weeks.

NCT ID: NCT00421993 Completed - Acne Vulgaris Clinical Trials

A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris

Start date: October 2006
Phase: Phase 3
Study type: Interventional

This is a multi-center, randomized, double-blind, parallel group study with 12 weeks of treatment of acne vulgaris. Efficacy and safety evaluations will be performed at Screening (safety only), Baseline and Weeks 1, 2, 4, 8 and 12. All Investigator's Global Assessment evaluators and lesion counters must be trained and approved by Galderma. The evaluator of a subject should remain the same during the study. The primary objective is to demonstrate the superiority in efficacy and assess safety of Adapalene/Benzoyl Peroxide Topical Gel (Adapalene/Benzoyl Peroxide Gel) versus Adapalene Topical Gel, 0.1% (Adapalene Monad); Benzoyl Peroxide Topical Gel, 2.5% (Benzoyl Peroxide Monad) and Topical Gel Vehicle (Gel Vehicle) in the treatment of acne vulgaris for up to 12 weeks.

NCT ID: NCT00419848 Recruiting - Acne Clinical Trials

the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris

Start date: August 2006
Phase: Phase 2
Study type: Interventional

a comparison of efficacy and adverse side effects occurrence of Doxycycline and Azithromycin in the management of moderate acne vulgaris

NCT ID: NCT00417456 Completed - Acne Vulgaris Clinical Trials

The Development and Evaluation of an "E-Visit" Program for the Management of Acne

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to test the efficacy, timeliness, and user satisfaction of an online "E-Visit" application that uses store-and-forward technology for acne patients requiring dermatologic care for their condition. Hypotheses: 1. That an "E-Visit" is an effective alternative to in-person clinic care for patients with mild to severe facial acne. 2. That providers and patients will be satisfied with this model. 3. That mean wait times for new and return visits will be reduced through the "E-Visit" model. 4. That this prototype for care will improve clinic workflow, offer additional patient access, and allow urgent cases to be seen earlier.

NCT ID: NCT00392223 Terminated - Acne Vulgaris Clinical Trials

Efficacy And Safety Of Azithromycin SR Compared With Minocycline In Acne

Start date: October 2007
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the clinical efficacy of azithromycin microspheres treatment in outpatients with moderate to severe inflammatory acne compared with first line treatment minocycline after 8 weeks of therapy

NCT ID: NCT00377000 Completed - Acne Vulgaris Clinical Trials

A Pilot, Multi-Center, Patient Preference Study Comparing Two Clindamycin/Benzoyl Peroxide Gels.

Start date: November 2005
Phase: Phase 4
Study type: Interventional

Evaluate patient preference factors comparing two clindamycin/benzoyl peroxide gels. One dispensed in a pump presentation, the other in a tube presentation.