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Acne Vulgaris clinical trials

View clinical trials related to Acne Vulgaris.

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NCT ID: NCT04648995 Recruiting - Acne Scar Clinical Trials

TheTreatment of Acne Scar Using UltraPulse CO2 Laser

Start date: December 11, 2020
Phase: N/A
Study type: Interventional

Purpose of the study is to assess the effect and evaluate topographic volume changes of UltraPulse at treating boxcar scars with different energy and the effect of UltraPulse at treating icepick scars.

NCT ID: NCT04596748 Recruiting - Acne Vulgaris Clinical Trials

Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris

Start date: May 11, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how probiotics affect sebum production and gut health in those with acne vulgaris.

NCT ID: NCT04582383 Recruiting - Acne Clinical Trials

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

Start date: March 30, 2022
Phase: Phase 4
Study type: Interventional

Acne is common illness of adolescents and young adults which is associated with substantial morbidity. While topical treatments are often sufficient for mild acne, moderate to severe acne often requires treatment with systemic medications such as oral antibiotics, hormonal therapies such spironolactone, and isotretinoin. Sebum overproduction is fundamental to the pathogenesis of acne with associated disordered keratinization and subsequent microbial colonization and inflammation resulting in the clinical manifestations of acne. Given the influence of hormones on sebum production, therapies that address these underlying hormonal factors such as spironolactone and oral contraceptive pills represent an underutilized treatment option for women with acne and could help decrease the use of long-term oral antibiotics in this patient population. The purpose of this trial is to evaluate the comparative effectiveness of spironolactone versus doxycycline hyclate (tetracycline class antibiotic) for women with acne.

NCT ID: NCT04538703 Recruiting - Acne Vulgaris Clinical Trials

Social Media Use of Acne Vulgaris Patients: Multicenter, Survey Work

Start date: March 1, 2020
Phase:
Study type: Observational

Acne Vulgaris is a chronic skin disease. However, chronic and repetitive due to the quality of life and psychological status of patients can affect. For this reason, patients carry out various research on their diseases on social media and follow programs on these issues in other media such as television and radio. However, there is no study on how much patients are interested in these publications, how much they trust them, and how they reach and organize information via social media. The aim of the study will be to clarify how and how patients with Acne Vulgaris use social media to obtain information about the diagnosis and treatment of their disease, the interaction of patient groups with each other, and how often social media is used, especially in which group of patients.

NCT ID: NCT04483063 Recruiting - Clinical trials for Arthroscopic Rotator Cuff Repair

Can Additional Preoperative Skin Cleaning on Face, Neck and Chest With Chlorhexidine Reduce Cutibacterium Acnes Contamination on Sutures in Arthroscopy Rotator Cuff Repair?

Start date: March 23, 2020
Phase: N/A
Study type: Interventional

The purpose of our study was to investigate whether preoperative skin cleaning on face, neck, and chest with chlorhexidine could reduce suture contamination of C. acnes in arthroscopic rotator cuff repair. We hypothesized that preoperative skin cleaning on face, neck and chest with chlorhexidine can reduce C. acnes contamination on sutures in arthroscopic rotator cuff repair.

NCT ID: NCT04214483 Recruiting - Acne Vulgaris Clinical Trials

A Pilot Study to Explore the Role of Gut Flora in Acne

Start date: March 2, 2020
Phase:
Study type: Observational

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.

NCT ID: NCT04213638 Recruiting - Acne Vulgaris Clinical Trials

Trial of Single Microneedle Radiofrequency for Moderate‐to‐Severe Acne Vulgaris

Start date: November 15, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to testify the efficacy of treating moderate‐to‐severe acne vulgaris with Single Microneedle Radiofrequency, and provide evidence for the hypothesis that "whether Single Microneedle Radiofrequency therapy could be an alternative to photodynamic therapy for moderate to severe acne vulgaris."

NCT ID: NCT04167982 Recruiting - Acne Clinical Trials

Efficacy and Safety of Painless 5-aminolevulinic Acid Photodynamic Therapy for Moderate and Severe Acne Vulgaris

Start date: March 28, 2020
Phase: N/A
Study type: Interventional

This study is being done to compare a new, continuous illumination and short Incubation time regimen of 5-aminolevulinic acid photodynamic therapy (painless ALA- PDT) to low-dose and conventional dose of oral isotretinoin for treatment of moderate or severe acne vulgaris. The hypothesis is that the painless ALA- PDT will be equally or more efficacious as oral isotretinoin, and taking effect more quickly with less adverse effect.

NCT ID: NCT04060160 Recruiting - Acne Vulgaris Clinical Trials

Acne Detection Software (AcneDect)

AcneDect
Start date: October 29, 2020
Phase:
Study type: Observational

This study is to create a self-learning software that can detect acne lesions. Patients take a picture of their face every single day for 3 months with a secure mobile phone and fill out a pre-designed questionnaire. After 3 months, the mobile will be collected back and the pictures will be evaluated by 3 dermatologists. The software is able to learn from the dermatologists' evaluation and -using machine learning- a mechanism that should be able to automatically detect acne to some extent will be established.

NCT ID: NCT04028401 Recruiting - Clinical trials for Cutibacterium Acnes Infection

Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients

OPRICA
Start date: June 19, 2020
Phase: Phase 3
Study type: Interventional

Infections on joint replacements remain one of the most serious complications of orthopaedic surgery. Despite improvements in skin preparation and antibiotic prophylaxis procedures, the risk of infection of joint prosthesis is still high, particularly for shoulder prostheses, especially in men. One of the bacteria most often involved in post-operative infections for shoulder prosthesis is Cutibacterium acnes (CA). This bacterium is one of the predominant bacteria in pilosebaceous units. Eradication of this micro-organism remains difficult despite the techniques used in the preoperative phase. The objective of this protocol is to evaluate the efficacy of applying a 5% benzoyl peroxide topical during the 5 days preceding the procedure in the surgical skin incision area, which is based on local acne treatment, on the reduction of the CA bacterial load in the dermis of the approach to shoulder arthroplasty in men.