Clinical Trials Logo

Clinical Trial Summary

Acne keloidalis nuchae (AKN) is one of the chronic forms of scarring folliculitis, affecting predominantly the occipital scalp, seen mostly in men of African descent. Duobrii has the advantage of being the only high potency topical steroid-retinoid combination approved by the FDA with dermatologic indication. Researchers are proposing the off-labeled use of Duobrii for the management of early-mild AKN. The research team hypothesizes that subjects will experience significant clinical improvement in lesion counts. Patients will be followed with visits scheduled at baseline, 4 weeks, 8 weeks, and 12 weeks. During these in-clinic visits, there will be surveys regarding the severity of AKN symptoms, photographs, and clinical assessments.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05608499
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact Giselle Singer
Phone 212-241-3288
Email giselle.singer@mssm.edu
Status Recruiting
Phase Phase 3
Start date October 26, 2022
Completion date October 2024

See also
  Status Clinical Trial Phase
Active, not recruiting NCT00757315 - NdYag Laser for Acne Keloidalis Nuchae N/A
Completed NCT02372786 - 7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream Phase 4
Completed NCT01548898 - The Efficacy of Laser Assisted Hair Removal in the Treatment of Acne Keloidalis Nuchae; a Pilot Study Phase 4
Terminated NCT00476697 - UVA1 Light for Scleroderma and Similar Conditions N/A
Completed NCT01328080 - Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy N/A