Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy

Acne Keloidalis Nuchae Clinical Trial

Official title:

Improving Acne Keloidalis Nuchae by Inducing Matrix Metalloproteinases in Vivo Using Targeted Ultraviolet-B Irradiation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01328080
• Other study ID #: NA_00035842
• Status: Completed
• Phase: N/A
• First received: March 31, 2011
• Last updated: May 19, 2014
• Start date: February 2011
• Est. completion date: August 2012

Study information

• Verified date: May 2014
• Source: Johns Hopkins University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

This study is being done to evaluate the effect of targeted UV-B (a component of sunlight) on the treatment of acne keloidalis nuchae (AKN, or razor bumps on the back of the neck). The investigators believe targeted UV-B is a safe and effective way to reduce the appearance of AKN.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 11
• Est. completion date: August 2012
• Est. primary completion date: August 2012
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• age 18 or over

• male gender

• African-American or other black ethnicity

• current diagnosis of acne keloidalis nuchae (razor bumps on back of neck)

Exclusion Criteria:

• allergy to lidocaine or numbing medicine

• history of increased sensitivity to sunlight, lupus, or porphyria

• current use of a drug that increases sensitivity to sunlight

Study Design

Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Acne Keloid
• Acne Keloidalis Nuchae

Intervention

Radiation:
• Targeted UV-B
Daavlin Lumera phototherapy device (290-320 nm), dosed by patients' individual minimal erythema dose (MED)

Locations

Country	Name	City	State
United States	Johns Hopkins Dept. of Dermatology	Baltimore	Maryland

Sponsors (2)

Lead Sponsor	Collaborator
Johns Hopkins University	Skin of Color Society

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage Change in Total AKN Lesions From Baseline to Week 16.	To determine if treatment of AKN with targeted ultraviolet B radiation will improve the clinical appearance of lesions.	Baseline to Week 16	No

External Links

•   Skin of Color Society (sponsor)