Effects of HMB Supplementation on Recovery Following ACL Surgery

Status Completed

Clinical Trial Summary

The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised. Reconstructive surgery is often necessary to repair the damage which is then followed by a regimen of physical therapy in order to regain full activity. Nutritional intervention after the surgery could help the patient maintain muscle mass during recovery, thus allowing for a quicker return to normal activity.

Clinical Trial Description

Beta-hydroxy-beta-methylbutyrate (HMB) is a nutritional supplement shown to improve muscle mass with exercise, and also in muscle loss conditions caused by a decrease in physical activity. Participants will be recruited who will undergo reconstructive surgery for a complete ACL tear and will then enter a standard physical therapy program during a six week recovery period. Subjects will receive either HMB or a placebo supplement during the recovery period. Muscle mass will be measured two weeks prior to the surgery and again after the recovery period using an InBody 720 body composition analyzer. Additionally, the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire will be administered as a measure of recovery and activity level during the study. ;

Study Design

Related Conditions & MeSH terms

ACL Injury
Anterior Cruciate Ligament Injuries

Clinical Trial Details

NCT number	NCT02602561
Study type	Interventional
Source	Metabolic Technologies Inc.
Contact
Status	Completed
Phase	N/A
Start date	November 2015
Completion date	August 2017

View Details

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