Abnormality in Synovial Tissue Clinical Trial
Official title:
Examination of Biopsies From Healthy Knee Joints for the Use of Research Activities in Inflammatory Joint Diseases
The purpose of the project is to examine what kind of molecular mechanism which causes inflammatory joint diseases. This examination is carried out by a collection and analysis of synovial tissues for patients without inflammatory joint diseases compared to the experienced equivalent biopsies from patients with inflammatory joint diseases.
Status | Terminated |
Enrollment | 43 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 18 Years to 90 Years |
Eligibility |
Inclusion Criteria: - Males and females > 18 years - Planned surgery for patients with meniscus or reconstruction of ligament Exclusion Criteria: - Employment at Aalborg University Hospital - Employment at Novo Nordisk A/S - An unsigned statement of consent - Current medical treatment resistant to a course of treatment, for example large doses of steroids |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
Denmark | Northern Orthopaedic Division, Aalborg University Hospital | Aalborg |
Lead Sponsor | Collaborator |
---|---|
Northern Orthopaedic Division, Denmark | Novo Nordisk A/S |
Denmark,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Adverse events as a measure of metabolism in normal tissue and inflammatory tissue. | Compare the normal metabolism in non-inflammatory tissue with biopsies of inflammatory diseases. | 7 years | Yes |
Secondary | Detect new objects for developing drugs. | Determine potential objects for medical intervention and development of drugs which affect the molecular mechanisms in relation to an inflammatory condition versus a normal metabolic condition. | 7 years | Yes |