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Weight Loss clinical trials

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NCT ID: NCT05987306 Recruiting - Clinical trials for Overweight and Obesity

A Self-compassion Focused Intervention for Internalized Weight Bias and Weight Loss

Start date: September 24, 2023
Phase: N/A
Study type: Interventional

The goal of clinical trial is to test a novel weight loss approach combining a standard weight loss and internalized weight bias intervention with self-compassion exercises in overweight adults with moderate to high levels of internalized weight bias. The main question[s] it aims to answer are: 1) Can participants lose significant weight loss and 2) significantly reduce internalized weight bias. Participants will take part in a 12 week novel weight loss approach combining a standard weight loss and internalized weight bias intervention with self-compassion exercises using videoconferencing software.

NCT ID: NCT05987085 Recruiting - Weight Loss Clinical Trials

Medical Weight Loss on Pelvic Floor Dysfunction

WLPFD
Start date: August 3, 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about the effect of medical weight loss on the symptom of pelvic floor dysfunction in obese and overweight women. The main question it aims to answer is: whether medical weight loss improves symptoms of pelvic floor dysfunctions in obese or overweight women.

NCT ID: NCT05982132 Recruiting - Weight Loss Clinical Trials

Weight Changes Among Martinican Prisoners

NUTRI-LAJÔL
Start date: January 11, 2023
Phase:
Study type: Observational

Assessment of body weight change among prisoners in Martinique between admission in jail and 3 months later expressed as a percentage of admission weight. Intensity of physical activities, nutrition intakes and psychological state are also studied to describe associated factors to body weight change.

NCT ID: NCT05981508 Recruiting - Obesity Clinical Trials

Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program

TEAM+
Start date: February 5, 2024
Phase: N/A
Study type: Interventional

The purpose of this research study is to test the feasibility and acceptability of an interactive counselor -led online family skills training as part of a behavioral weight loss program for Black Adults.

NCT ID: NCT05969639 Recruiting - Obesity Clinical Trials

Improving Dietary Habit and Weight Loss in Young Adults With Overweight and Obesity: The Healthy Eating for Young Adults (HEYA) Study

Start date: July 25, 2023
Phase: N/A
Study type: Interventional

This study aims to examining the effectiveness of a psychoeducational program (Healthy Eating in Young Adults; HEYA) on improving the dietary habits and body composition (e.g. weight and percentage fat mass) in young adults in Singapore.

NCT ID: NCT05952882 Not yet recruiting - Obesity Clinical Trials

Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility

Start date: November 1, 2023
Phase: Phase 3
Study type: Interventional

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age and one of the leading causes of infertility. PCOS and obesity affect up to 12.5% - 48.3% Asian women, increase incidence of impaired glucose tolerance, type 2 diabetes and aggravate insulin resistance, cause ovulatory dysfunction and menstrual disorders, and negatively impact outcomes of Assited Reproductive Technology (ART), with higher miscarriage rate when receiving ART. Weight loss decrease insulin resistance and hyperandrogenism, improve ovulation rate and menstrual cycle, significantly higher conception and live birth rates. Weight loss prior to IVF procedures has been associated with significantly improved pregnancy rates (PR) and live birth rates. Furthermore, a decreased number of IVF cycles required to achieve a pregnancy has also been reported after weight loss interventions. Based on the principles of fetal programming, improving a lifestyle before conception might lead to improved longterm health of the offspring. Studies on the effect of anti-obesity medication combined with lifestyle changes on body weight and composition and metabolic - endocrine parameters and pregnancy rate in obese women diagnosed with PCOS are lacking. There is a growing need to develop pharmacologic interventions to improve metabolic function in women with polycystic ovary syndrome (PCOS).

NCT ID: NCT05944549 Recruiting - Weight Loss Clinical Trials

Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families

Start date: May 12, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect on weight and metabolic outcomes of an enhanced intervention, comprised of evidence-based financial coaching plus a lifestyle intervention vs. the lifestyle intervention alone

NCT ID: NCT05942326 Recruiting - Weight Loss Clinical Trials

Sleep Goal-focused Online Access to Lifestyle Support

SGOALS
Start date: September 21, 2023
Phase: N/A
Study type: Interventional

The overall goal of the study is to develop a novel weight loss intervention for postpartum people by providing strategies to improve sleep, diet, and physical activity behaviors. In this study, we will recruitment and enroll 40 postpartum people and randomize them to receive the Sleep GOALS intervention or education control to evaluate the intervention's feasibility, acceptability, and preliminary efficacy.

NCT ID: NCT05942287 Recruiting - Obesity Clinical Trials

The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.

SLEnDR
Start date: May 24, 2023
Phase: N/A
Study type: Interventional

This study looks at the effects of weight loss in people who have heart failure with reduced ejection fraction (HFpEF) and are overweight or obese. The main questions it aims to answer are whether weight loss in this group of people improves: - The heart's shape and how well it pumps blood - The person's quality of life and how much they can exercise Participants will attend 2 study visits, separated by 3-6 months. The intervention period takes place in between the 2 study visits. Each study visit may involve measurements including: Symptom and quality of life questionnaires Body measurements such as height and weight Blood tests Ultrasound scans of the heart (echocardiogram) Magnetic Resonance Imaging (MRI) scans of the heart 6 minute walk test Participants are randomly allocated (in other words, by lottery) to either 'diet' or 'control' groups. The control group will continue standard care. The diet group will be enrolled in a weight loss program supervised by the study team. Participants in the diet group will replace their usual meals with meal replacement products specifically designed to deliver a low calorie diet for weight loss. The products will consist of formula soups, shakes and porridges. This diet would last 8 weeks, followed by a guided period of food reintroduction and maintenance.

NCT ID: NCT05941871 Recruiting - Clinical trials for Overweight and Obesity

Chronotype-adapted Diet and Weight Loss

CHRONODIET
Start date: March 6, 2023
Phase: N/A
Study type: Interventional

In humans, prolonged alterations in the circadian rhythm have been linked to cognitive impairments, premature ageing, and oncological and metabolic disorders such as diabetes and obesity. Obesity, in particular, is an ever-increasing condition with innumerable deleterious effects on human health. In recent years, studies have shown a relationship between a person's chronotype (morning or evening) and eating habits, as well as the importance of adapting these habits to physiological rhythms. Furthermore, it has been suggested that customising the caloric distribution of meals according to personal circadian rhythms may influence body weight and be one of the strategies to control overweight and obesity. In spite of the strong interest in this topic and the increasing number of observational studies conducted, there is currently a lack of intervention studies evaluating whether a low-calorie diet that takes into account the individual chronotype may be more effective than a standard low-calorie diet in the treatment of overweight and/or obesity.