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Venous Leg Ulcer clinical trials

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NCT ID: NCT02482038 Completed - Venous Leg Ulcer Clinical Trials

Geko Venous Leg Ulcer Study

Start date: September 2016
Phase: N/A
Study type: Interventional

This study is designed to look at the effect of the geko device on the circulation in lower limbs of participants with venous leg ulcers.

NCT ID: NCT02470806 Completed - Clinical trials for Diabetic Foot Ulcers

Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPWT)

NPWT
Start date: July 2, 2015
Phase: N/A
Study type: Interventional

The aim of this study is to compare the clinical efficacy of two types of NPWT systems; the traditional negative pressure wound therapy (tNPWT) system and the single-use negative pressure wound therapy (PICO) system.

NCT ID: NCT02422017 Completed - Venous Leg Ulcers Clinical Trials

Topical Timolol Benefit in Venous Ulcers

EETUV
Start date: April 2015
Phase: Phase 2
Study type: Interventional

Background: Venous Leg ulcers are a frequent pathology in dermatology and complex in their management. At the origin of high health costs and strong repercussions on quality of life for patients, they require long management and may be subject to possible complications. In spite of appropriate treatment, 50-60% of these ulcers are not healed at 24 weeks. Purpose: Topical beta adrenergic antagonists have shown efficacy in wound healing. The purpose of this study is to evaluate the efficacy and safety of treatment of chronic venous ulcers with topical timolol.

NCT ID: NCT02395302 Completed - Venous Leg Ulcer Clinical Trials

Evaluation of a Dual Action Pneumatic Compression System: Tolerance and Comfort in Patients With Venous Leg Ulcers

Start date: December 2014
Phase: N/A
Study type: Interventional

The purpose of the study is to assess treatment tolerance and comfort in chronic VLUs after 4 weeks of treatment using a dual action pneumatic compression device.

NCT ID: NCT02364921 Completed - Venous Ulcers Clinical Trials

Effectiveness of Double-layer Compression Therapy in the Healing of Chronic Venous Ulcers in Primary Health Care

Start date: June 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of a multilayer compression bandage (two layers), compared with the crepe bandage, on healing of venous leg ulcers, in patients attended in nursing Primary Care Health Centres, at 12 weeks follow-up.

NCT ID: NCT02222467 Completed - Venous Leg Ulcers Clinical Trials

Safety Evaluation of the KLOX BioPhotonic System in Venous Leg Ulcers

Start date: November 2012
Phase: N/A
Study type: Interventional

The primary objective of these case series is to evaluate the safety and tolerability of the KLOX BioPhotonic System as adjunctive therapy to Standard Of Care (SOC) in patients with venous leg ulcers.

NCT ID: NCT02167815 Completed - Clinical trials for Venous Leg Ulcer (VLU)

A Multicenter, Post Marketing Clinical Follow up (PMCF) Investigation to Evaluate the Performance and Safety of a Soft Silicone Foam Dressing and to Evaluate the Performance of Standard Care in Exuding Venous Leg Ulcers

Start date: May 2014
Phase: N/A
Study type: Interventional

This investigation is a Post Marketing Follow-Up Study for Mepilex XT conducted as part of Mölnlycke Health Care's quality system. The primary objective is to evaluate the performance of the dressing when used as intended on exuding Venous Leg Ulcers (VLUs) in the inflammatory and granulating stages of the wound healing process.

NCT ID: NCT02158806 Completed - Venous Leg Ulcer Clinical Trials

Low Dose Aspirin for Venous Leg Ulcers

Aspirin4VLU
Start date: March 2015
Phase: Phase 3
Study type: Interventional

Venous leg ulcers (VLU) are the most common leg ulcer, can be painful, and limit work, lifestyles and activity, especially in older patients. There are few effective treatments - compression therapy (tight bandaging or stockings) helps healing, but about half the people with a VLU remain unhealed even after 12 weeks of treatment. Research suggests taking aspirin as well as using compression may speed up healing for VLU, but the current evidence is not enough to change clinical practice. We will conduct a randomised controlled trial to test whether using low dose aspirin (150 mg daily or placebo) really does speed up healing.

NCT ID: NCT02104180 Completed - Venous Leg Ulcer Clinical Trials

Evaluation of Pain Associated With the Removal of Wound Dressing During Care of Venous Leg Ulcer. Comparison of the Efficacy and Safety of Two Dressings Urgotul and TulleGras

Start date: February 2014
Phase: N/A
Study type: Interventional

Evaluation of the non-inferiority of TulleGras M.S.® versus Urgotul® in pain associated with removal of wound dressing during care of venous leg ulcer

NCT ID: NCT02092870 Completed - Diabetic Foot Clinical Trials

Adipose Derived Regenerative Cellular Therapy of Chronic Wounds

Start date: September 2013
Phase: Phase 2
Study type: Interventional

Our study aims to explore the effects of Adipose Derived Stem Cells (ASCs) on chronic wounds.