Venous Thromboembolism Clinical Trial
Official title:
Using Inflammatory Markers to Predict the Development and Outcome of Venous Thromboembolism in an Intensive Care Unit
Venous thromboembolism (VTE) is one of the major public health problems in Western country.
More than 100,000 Americans die each year from VTE. VTE is also a common complication of
critical illness,1-2 and probably related to poor outcome in this patient group. Although
there are guidelines about VTE prophylaxis in acutely ill medical patients and patients in
medical ICU3, they are overlooked in our daily practice frequently in our country. There are
many reasons for our common practice, including inadequate knowledge for the ICU physicians,
more patients with bleeding tendency in ICU and low prevalence of VTE in our (eastern)
country. However, the true prevalence of VTE in ICU and if thromboprophylaxis still needed
in certain high risk patients are not unknown. Besides, if there is a difference in the VTE
rate between western and eastern patients, what is the underlying mechanism? The major
objective of this application is to answer the first part of the problem, i.e. to delineate
the scope of this problem.
The specific aims of this application are as follows:
- prevalence of venous thromboembolism in ICU in Taiwan
- specific risk in subgroups of ICU patients
- prevalence and risk factors for silent pulmonary embolism
n/a
Observational Model: Case Control, Time Perspective: Prospective
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