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Urinary Bladder Neoplasms clinical trials

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NCT ID: NCT02238886 Completed - Bladder Cancer Clinical Trials

Radical Cystectomy, Nutrition and Convalescence

Start date: May 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a goal directed nutritional intervention can reduce the convalescence period for patients undergoing radical cystectomy (RC). The aim is to examine the effect on quality of life of a standard nutritional strategy of resting the bowel till clear signs of bowel recovery and feeding orally after bowel recovery versus a goal-directed nutritional intervention combining oral intake and parenteral nutrition, in patients undergoing RC.

NCT ID: NCT02217891 Completed - Breast Cancer Clinical Trials

IFACT: Incidental Findings in Advanced Cancer Therapy

IFACT
Start date: August 2014
Phase:
Study type: Observational

The proposed study, IFACT - Incidental Findings in Advanced Cancer Therapy, will address this research gap by examining MSK patients' attitudes, preferences, and information needs regarding incidental findings arising from tumor genomic profiling.

NCT ID: NCT02214602 Completed - Clinical trials for Carcinoma of Urinary Bladder, Superficial

Value of Immediate Post-operative Intravesical Epirubicin in Intermediate&High Risk Non Muscle Invasive Bladder Cancer

NMIBCIVT
Start date: July 2014
Phase: Phase 4
Study type: Interventional

The aim of the study is to test the value of immediate post-operative intravesical instillation of epirubicin in patients with intermediate and high risk non muscle invasive bladder cancer (NMIBC).

NCT ID: NCT02203136 Completed - Bladder Cancer Clinical Trials

Improving Clinical Staging for Muscle Invasive Bladder Cancer Through Molecular Profiling and Improved Imaging

Start date: June 25, 2014
Phase:
Study type: Observational

The goal of this research study is to improve detection of cancer outside of the bladder through genetic testing and improved imaging.

NCT ID: NCT02197897 Completed - Bladder Cancer Clinical Trials

Evaluation the Treatment of Tamoxifen of Low/Intermediate Risk Bladder Tumors

BCTamoxifen
Start date: April 1, 2015
Phase: Phase 2
Study type: Interventional

Evaluate the treatment of tamoxifen of low/intermediate-risk bladder tumors

NCT ID: NCT02188446 Completed - Bladder Cancer Clinical Trials

Intensive Smoking and Alcohol Cessation Intervention in Bladder Cancer Surgery Patients

STOP-OP
Start date: November 2014
Phase: N/A
Study type: Interventional

Radical cystectomy provides the best cancer-specific survival for muscle-invasive urothelial cancer. However the postoperative morbidity remains at 11-68 %. Smoking and alcohol consumption above two drinks per day is associated with an increased risk of postoperative morbidity. Six-eight weeks of smoking and alcohol abstinence prior to elective surgery is recommended to reduce this risk, but for cancer patients the preoperative period is often very short. This randomised clinical trial (STOP-OP) will reach a conclusion on the effect of a new Gold Standard Programme for both smoking and alcohol cessation Intervention using the Gold Standard Programme (GSP) on the frequency and severity of postoperative complications after bladder cancer surgery.

NCT ID: NCT02177695 Completed - Bladder Cancer Clinical Trials

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer

COXEN
Start date: August 28, 2014
Phase: Phase 2
Study type: Interventional

The primary focus of this study is to see if looking at tumor biomarkers using a program called coexpression extrapolation or "COXEN" may predict a patient's response to chemotherapy before surgery.

NCT ID: NCT02149862 Completed - Bladder Cancer Clinical Trials

FIRBladd - Use of Infrared Spectroscopy in the Diagnosis of Bladder Tumors

FIRBladd
Start date: May 2014
Phase: N/A
Study type: Interventional

The purpose of this study is too assess infrared spectroscopy ability to discriminate urine of a patient affected by bladder cancer from urine of reference patient.

NCT ID: NCT02145871 Completed - Bladder Cancer Clinical Trials

A Prospective Randomized Controlled Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Radical Cystectomy

Start date: May 21, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to help us learn what is the best amount of fluid to give to patients during bladder surgery in order to avoid delayed bowel function after surgery, which could prolong hospital stay.

NCT ID: NCT02139371 Completed - Breast Cancer Clinical Trials

Evaluation of a New Radiotracer (64Cu-DOTA-AE105) for Diagnosing Aggressive Cancer With Positron Emission Tomography

Start date: May 2014
Phase: Phase 0
Study type: Interventional

The primary objective of the study is to test a new radiotracer called 64Cu-DOTA-AE105 for PET imaging of uPAR (urokinase plasminogen activator receptor). The tracer has the potential of identifying the invasive cancer phenotype, thereby distinguishing between aggressive and less aggressive tumors. This is a first in human study to test the radiotracer in cancer patients. The biodistribution and tumor uptake will be evaluated by repeated PET imaging (1,3 and 24 hours post injection).