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Total Knee Replacement clinical trials

View clinical trials related to Total Knee Replacement.

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NCT ID: NCT03088358 Completed - Clinical trials for Total Knee Replacement

Safety and Efficacy of TeaRx Xa Factor Direct Inhibitor Versus Enoxaparin as a Venous Thromboembolic Events (VTE) Prevention Following Total Knee Replacement

Start date: August 2013
Phase: Phase 2
Study type: Interventional

To evaluate influence of therapy on the following efficacy and safety parameters in different TeaRx dose groups and Enoxaparin group: - Total venous thromboembolic events (VTE), which includes confirmed deep venous thrombosis (DVT), nonfatal pulmonary embolism (PE), and total mortality - Incidence of DVT (total, proximal, distal) - Incidence of nonfatal PE - Incidence of symptomatic VTE (DVT, PE) - VTE caused mortality - Non-VTE caused mortality - Incidence of all hemorrhagic complications - Incidence of major and clinically relevant non-major bleeding - Adverse events (AEs) and serious adverse events (SAEs) from subject complaints, physical examination, vital signs, laboratory results

NCT ID: NCT02982785 Completed - Osteoarthritis Clinical Trials

Knee Replacement Outcome Predicted by Physiotherapists

Start date: December 2016
Phase:
Study type: Observational

The aim is to assess if physiotherapists attending inpatients at elective orthopaedic wards can predict the future course (post hospitalisation) of recovery of patients undergoing KA. The prediction is made at hospital discharge using a 1-10 numerical rating scale (1=poor prognosis; 10=best prognosis). To identify candidate prognostic factors, the therapist are asked to qualify their prognosis narratively, by listing at least 3-5 factors that they consider important for their projected prognosis score. There will be no maximum number of factors the physiotherapist can list.

NCT ID: NCT02914210 Completed - Clinical trials for Total Knee Replacement

Virtual vs. Traditional Physical Therapy Following Total Knee Replacement

Start date: October 2016
Phase: N/A
Study type: Interventional

The goals of this research study are the following: 1. To compare the effects of tele-rehabilitation-supported physical therapy versus traditional home and/or clinic-based physical therapy for total knee replacement (TKR) on 90-day health service use costs. 2. To compare tele-rehabilitation-supported physical therapy and traditional physical therapy on patient-centered outcomes 3. To explore whether individual patient characteristics are associated with differential improvement from 6 to 12 weeks assessed by patient-reported outcomes.

NCT ID: NCT02873637 Completed - Clinical trials for Total Knee Replacement

Adductor Under Sartorial Canal Catheter (KTT) Versus Femoral Catheter (KTF) in a Quick Rehabilitation Process After Total Knee Replacement

KTSS
Start date: January 2017
Phase: N/A
Study type: Interventional

The main objective of this study is to show that postoperative Total Knee Replacement (TKR), an analgesic perineural catheter in position under sartorial (KTSS) best preserves motor quadriceps femoral perineural catheter that (KTF) infused with even low doses of local anesthetics, this motor being evaluated by a semi quantitative simple clinical test locking of the knee feasible at the bedside. Patients will be randomized in two arms: - catheter in position under sartorial (experimental group) - femoral catheter (control group)

NCT ID: NCT02817737 Recruiting - Clinical trials for Total Knee Replacement

Pre-operative Radiological Measurement to Assess Femur Rotational Alignment

Start date: April 2016
Phase: N/A
Study type: Observational

Purpose: This study outlines the benefits of the proximal tibia angle (PTA) in evaluation of the pre-operative individual condylar twist angle (CTA) in total knee arthroplasty. Methods: Condylar twist angle and proximal tibia angle were obtained from 33 female healthy participants using computed tomography (CT). The CTA, angle between clinical transepicondylar axis and posterior condylar line were measured. The PTA is the angle formed between the mechanical axis of the tibia and tibia plateau line. The correlation between the CTA and the PTA was analyzed statistically with the linear regression.

NCT ID: NCT02707419 Completed - Clinical trials for Total Knee Replacement

Action Observation in Knee Replacement

Start date: April 2014
Phase: N/A
Study type: Interventional

Postoperative rehabilitation is required for a successful outcome following total knee arthroplasty. Traditionally rehabilitative programs aim to increase range of motion, to strengthen quadriceps, to restore normal gait, and to recover independence in activities of daily living. In the last decade action observation treatment, in addition to conventional physiotherapy has been proposed as a treatment method in rehabilitative medicine. There is growing evidence of the applicability of action observation training in rehabilitative medicine, indeed it has been applied in the rehabilitation of stroke of Parkinson disease of cerebral palsy and of aphasia. Nevertheless those are small studies and one of them included a mixed population of hip and knee arthroplasty.

NCT ID: NCT02706990 Completed - Clinical trials for Total Knee Replacement

Fluoroscopic Analysis of Total Knee Replacement With a Kinematic Retaining or a Posterior Stabilized Design

Start date: January 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the in vivo kinematics of TKA performed with two different prosthesis: a kinematic retaining (Physica KR) and a posterior-stabilized (Physica PS) design by means of fluoroscopic analysis during activities of daily living (rising from a chair, stairs climbing, leg extension). In comparison with asymptomatic knee. Patterns of femoral rollback will be analyzed to assess if they are motor-task dependent and correlated with clinical outcomes.

NCT ID: NCT02685735 Terminated - Pain Clinical Trials

Predicting, Understanding and Speeding Recovery After TKA

Start date: June 2, 2016
Phase: Phase 4
Study type: Interventional

The objective of this research study is to better understand patterns of recovery after Total Knee Arthroplasty (TKA) amd Total Hip Replacement (THA). The study will evaluate how pain, activity and cognitive (i.e., thinking style) responses determine patterns of recovery, and the study will evaluate the efficacy of gabapentin versus placebo for improving recovery after surgery.

NCT ID: NCT02673892 Terminated - Clinical trials for Chronic Obstructive Pulmonary Disease

Patient Oriented Discharge Summary Impact Study

PODS
Start date: February 2016
Phase: N/A
Study type: Interventional

Improving the patient experience has become a major focus of quality improvement efforts in Ontario and in health systems worldwide. However, our existing knowledge base is relatively under-developed, particularly in how patients experience care as they transition from one care setting to another and the relationship between patient experience and clinical outcomes. The Patient Oriented Discharge Summary (PODS) is a discharge instruction tool created by patients, caregivers, health-care providers and design experts. It provides a written template for providers to engage patients and caregivers when reviewing important instructions on medications, activity and diet restrictions, follow-up appointments and worrisome symptoms warranting emergency care following admission to hospital. The PODS also uses plain and simple wording, large fonts, pictograms, and includes white space for patients to take notes and provides the option for translation of major headings into the most common spoken languages. The PODS impact study will study the impact of using the PODS versus usual discharge instructions on patient experience and health outcomes in a provincial-wide randomized study across acute care and rehabilitation hospitals.

NCT ID: NCT02670499 Completed - Clinical trials for Total Knee Replacement

Study Comparing GAP-Flex to CPM Therapy in Treatment of TKR

GAP-Flex
Start date: November 18, 2015
Phase: N/A
Study type: Interventional

Post Market TKR study