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Surgical Procedure, Unspecified clinical trials

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NCT ID: NCT03854669 Recruiting - Pain, Postoperative Clinical Trials

Experimental Pain Reporting Accuracy and Clinical Post-operative Pain

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Pain is a subjective experience that differs in intensity from one person to another. Appropriate medical care relies on an accurate assessment of the patients' condition. However, when it comes to subjective assessment, accurate assessment is a challenge. The most common tools used to estimate pain intensity depend on patient pain reports on a numerical pain scale (NPS) or a similar scales. Although these tools are widely used, there is a tendency to ignore the fact that the reliability and accuracy of pain reports are strongly influenced not only by the measuring instrument, but also by the person who uses it. A method has recently been developed to assess the accuracy of pain reports, and in a series of studies it has been found that the more accurate a person is in pain reports in response to stimulation,the smaller his placebo effect is .The aim of the study is to investigate whether assessing the accuracy of a person's pain reports can predict who will experience intensified post-operative pain and post-operative analgesic medications intake.The study will include 40 patients undergoing elective head & neck surgery. The study will be conducted prospectively and will include one pre-operative meeting to assess the accuracy of pain reports using the Focused Analgesia Selection Test (FAST). Patients will also complete pain-related psychological questionnaires during the session. In addition, post-operative pain measurements (NPS), and the use of pain relieving drugs (SOS) will be taken until release.

NCT ID: NCT03790930 Recruiting - Clinical trials for Surgical Procedure, Unspecified

Deep-learning Based Classification of Spine CT

DETECT
Start date: February 22, 2019
Phase:
Study type: Observational

It is time-consuming for spine surgeons or radiologists to conduct manual classifications of spinal CT, which may also be correlated with high inter-observer variance. With the development of computer science, deep learning has emerged as a promising technique to classify images from individual level to pixel level. The main of the study is to automatically identify and classify the lesions, or segment targeted structures on spinal CT with deep learning.

NCT ID: NCT03776591 Active, not recruiting - Quality of Life Clinical Trials

Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer

D3/CME
Start date: September 1, 2016
Phase: N/A
Study type: Interventional

The primary focus in this study is to investigate and improve the surgical technique. In addition the collection of clinical data during diagnostic and follow up and the collection of tumor and blood gives us the opportunity to investigate tumor biology and its relevance in terms of determine appropriate treatment strategy both surgically and oncological and to assess and predict treatment outcome. The aim of this study is to compare short and long-term outcomes between open D3 and laparoscopic CME (complete mesocolic excision) with CVL (central vascular ligation) right colectomy for right-sided colon cancer. Our primary hypothesis is that laparoscopic surgery improves quality of life by reducing pain, postoperative complications and thereby reduces hospital stay and convalescence. On the other hand it is to prove non-inferiority of the laparoscopic group compared to the open group by means of oncological outcome (survival, recurrence). Secondary aim is to evaluate surgical quality by comparing actual vascular stump length between the two groups by postoperative CT and compare number of lymph nodes removed with the specimen. With the use of liquid biopsy we want to detect circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) and evaluate their value as tumor markers by comparing the prognostic and predictive value. The hypothesis is that ctDNA and CTCs are more sensitive than standard parameters and imaging (CT CEA).

NCT ID: NCT03749304 Completed - Clinical trials for Surgical Procedure, Unspecified

Monitoring Analgesia by ANI (Analgesia The Nociception Index)

ANI-MICI
Start date: March 16, 2014
Phase: N/A
Study type: Interventional

The objective of this research is to study the variations of the ANI(Analgesia The Nociception Index) according to 2 periods: the "NoStim" period before surgical incision under general anesthesia and the period of hemodynamic reactivity "ReactHemo" peroperative. This period is defined by a 20% increase in FC and / or PAS (the only gold standard today).

NCT ID: NCT03684720 Active, not recruiting - Clinical trials for Surgical Procedure, Unspecified

Using 'Guided-Discovery-Learning' to Optimize and Maximize Transfer of Surgical Simulation

GDLEFFICACY
Start date: October 2, 2018
Phase: N/A
Study type: Interventional

The study is a randomized experimental study comparing two forms of learning; guided-discovery-learning and traditional instructional learning. Recruiting sixty-four participants, the investigators plan on comparing these two groups through a procedural skill in the form of suturing. In the case of guided-discovery-learning, the group will be allowed a discovery phase before instruction. In contrast, the control group will receive traditional instruction-lead-learning, in which a teacher teaches the participants a skill, and afterwards the participants practice it. After the teaching session, both groups will undertake a post-test of skill-level. A week later both groups will undertake a test for the execution of the learned suturing skill to a more complex version of the original task (Near-transfer). They will also undergo a test for the ability to transfer their learning to a new skill (i.e. preparation for future learning), in this case a new suture (Far-transfer). By filming these tests and having a blinded expert rater score them, the investigators will be able to get a measurement of attained transfer of skill-level throughout the procedures. The investigators hypothesis is that, the participants in the Guided-discovery-group will have an equal score to that of the traditional-learning group in the ability to obtain a skill and transfer it to a more complex version. Furthermore, the investigators hypothesize that the Guided-discovery-group will score better than the traditional-learning group in the case of transferring the procedural knowledge to learning a new skill. As well as testing the efficacy of guided-discovery-learning on a procedural skill, the investigators wish to investigate how and why it works. By filming a subset of participants in each group, as well as using questionnaires, and focus-group interviews the investigators will explore how participants interact in this different learning-environment compared to the traditional instructional learning-environment.

NCT ID: NCT03681990 Completed - Clinical trials for Surgical Procedure, Unspecified

In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area

Start date: June 6, 2017
Phase: Phase 2
Study type: Interventional

This study evaluates reduction of resident flora produced by the test product within a defined prepped area of skin.

NCT ID: NCT03603574 Completed - Clinical trials for Surgical Procedure, Unspecified

Epidural Waveform Analysis for Thoracic Epidural Blocks

Start date: July 30, 2018
Phase: N/A
Study type: Interventional

Epidural waveform analysis (EWA) provides a simple confirmatory adjunct for loss-of-resistance (LOR): when the needle/catheter tip is correctly positioned inside the epidural space, pressure measurement results in a pulsatile waveform. Epidural waveform analysis can be carried out through the tip of the needle or the catheter. In this randomized trial, the objective is to compare epidural waveform analysis through the needle (EWA-N) and through the catheter (EWA-C) for thoracic epidural blocks.

NCT ID: NCT03585439 Completed - Clinical trials for Surgical Procedure, Unspecified

Isthmic Spondylolisthesis Treated With Combined Approach: Clinical and Radiological Outcomes

SPLAC
Start date: June 28, 2018
Phase:
Study type: Observational

This study aims to evaluate clinical and radiological outcomes of isthmic spondylolisthesis surgically treated with combined approach. The goal is to demonstrate that it is a safe and efficient technique to treat isthmic spondylolisthesis. There is very little literature concerning this procedure.

NCT ID: NCT03556696 Completed - Clinical trials for Surgical Procedure, Unspecified

Automatic Remifentanil Administration Guided by ANI During Propofol Anesthesia

ANI-LOOP
Start date: June 27, 2018
Phase: N/A
Study type: Interventional

Prospective Randomized Monocentric Clinical Trial during propofol anesthesia. The aim of the study is to test whether the use of a medical device designed to automatically administer remifentanil during surgery based on expert rules and continuous reading of heart rate, blood pressure and the Analgesia Nociception Index results in lower overall remifentanil administration versus standard practice.

NCT ID: NCT03537352 Completed - Clinical trials for Surgical Procedure, Unspecified

Shared Decision Making in a General Hospital

Start date: May 14, 2018
Phase:
Study type: Observational

A pilot cross-sectional study will investigate the differential effect of the type of disorder (surgical versus non-surgical) on the scores of the 9-item shared decision making questionnaire.