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Impact of Nimodipine on Sublingual Microcirculation in Patients With Hemorrhage - a Prospective Monocentric Observational Study

Subarachnoid Hemorrhage Clinical Trial

Official title:
Impact of Nimodipine on Sublingual Microcirculation in Patients With Subarachnoid Hemorrhage - a Prospective Monocentric Observational Study

Clinical Trial Summary

Nimodipine can increase Functional Capillary Density (FCD) as a parameter of the sublingual microcirculation in patients with subarachnoid hemorrhage (SAH) compared to patients without nimodipine.

Clinical Trial Description

SAH group - in patients with SAH and documented vasospasms by digital subtraction angiography (DSA) of trans-cranial doppler imaging (TCD) of arteria cerebri media nimodipine is indicated because it is proven to improve the clinical outcome. The disfunction of cerebral microcirculation in rats with SAH has been documented [1-6]. Changes in sublingual microcirculation in patients with SAH with documented vasospasms with nimodipine has not been described. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04311840
Study type Observational
Source University Hospital Hradec Kralove
Contact David Astapenko, M.D., Ph.D.
Phone +420608177374
Email david.astapenko@fnhk.cz
Status Recruiting
Phase
Start date November 1, 2019
Completion date December 31, 2022
View Details
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