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Clinical Trial Summary

This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship. The chosen experimental design integrates biomechanical analyses, neuropsychological assessments, and brain imaging techniques to determine the impact of post-stroke cognitive impairment severity on two forms of motor learning (explicit and implicit) and examine the role of the dorsolateral prefrontal cortex in the relationship between cognition and explicit motor learning. Ultimately, this work may lead to the development of a more comprehensive, effective treatment approach to improve walking dysfunction in older adults post-stroke.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04829071
Study type Interventional
Source University of Southern California
Contact Kristan Leech, PT, DPT, PhD
Phone (323) 442-1583
Email kleech@pt.usc.edu
Status Recruiting
Phase Early Phase 1
Start date January 16, 2023
Completion date August 14, 2025

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