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Clinical Trial Summary

To date, the time window of intravenous thrombolysis is limited within 4.5 hours of stroke onset. Although EXTEND study has proved that intravenous thrombolysis can be extended from 4.5 to 9 hours, but the eligible patients must be selected by CTP. Thus, it is of clinical importance how to extend the time window of intravenous thrombolysis, which can benifit more patients. The current trial aims to investigate the effect of intravenous thrombolysis with TNK from 4.5 to 6 hours in ischemic stroke with help of Butyphthalide, which was found to be neuroprotective.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05189509
Study type Interventional
Source General Hospital of Shenyang Military Region
Status Not yet recruiting
Phase Phase 2
Start date January 15, 2022
Completion date December 30, 2022

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