Other Clinical Trial - Comparison of Vascular Access in STEMI

Status Completed

Clinical Trial Summary

Distal radial access (DRA) has recently introduced and previous studies have demonstrated that it is feasible option, showing several advantages including less bleeding and access-site complications over proximal radial access (PRA). Previous study reported the feasibility of DRA as an alternative option for primary percutaneous coronary intervention (PCI) in STEMI patients without major complication. However, comparison study of each vascular access for primary PCI have not been conducted until now. Here, The investigators aim to compare the DRA, PRA and femoral access (FA), in terms of feasibility and safety, in patients with STEMI. This is a retrospective study with patients who underwent primary PCI for STEMI between March 2020 to May 2021. The primary outcome of this study is the access-site complication including major bleeding requiring transfusion or surgery, hematoma and arterial occlusion.

Clinical Trial Description

Recently, DRA has gained the interest of interventional cardiologists and previous studies have demonstrated several advantages including patient and operator comfort, shorter hemostasis duration, less bleeding, and access-site complications over PRA. More recently, randomized trial demonstrated that DRA prevents radial artery occlusion after the procedure compared with PRA. From this perspective, DRA could be considered an alternative access route for primary PCI in selected STEMI patients using potent P2Y12 inhibitors such as ticagrelor or prasugrel, or glycoprotein IIb/IIIa inhibitors. ;

Study Design

Related Conditions & MeSH terms

Infarction
Myocardial Infarction
ST Elevation Myocardial Infarction

Clinical Trial Details

NCT number	NCT04941638
Study type	Observational
Source	Yonsei University
Contact
Status	Completed
Phase
Start date	June 17, 2021
Completion date	June 29, 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05601999` - Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction	Phase 3
Recruiting	`NCT06147986` - Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells as an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients	Phase 2
Not yet recruiting	`NCT05881382` - Dutogliptin in Co-administration With Filgrastim in Early Recovery Post-myocardial Infarction	Phase 3
Enrolling by invitation	`NCT02615015` - SNPs in the DNase 1 Gene Impair Its Activity and Are Increased in a STE-ACS Patient Cohort Compared to Healthy Controls	N/A
Recruiting	`NCT05812963` - IVUS Versus FFR for Non-infarct Related Artery Lesions in Patients With Multivessel Disease and Acute STEMI	N/A
Recruiting	`NCT05554588` - Intrathrombus Thrombolysis Versus Aspiration Thrombectomy During Primary PCI	N/A
Recruiting	`NCT05450757` - Shanghai ST-segment Elevation Myocardial Infarction Cohort
Active, not recruiting	`NCT03278509` - Evaluation of Decreased Usage of Betablockers After Myocardial Infarction in the SWEDEHEART Registry (REDUCE-SWEDEHEART)	Phase 4
Not yet recruiting	`NCT03263468` - Revascularization StrategIes for ST Elevation Myocardial Infarction Trial	N/A
Not yet recruiting	`NCT03266328` - Procedure and In-hospital Outcome of Patients Under 40 Years Old Undergoing Primary Percutaneous Coronary Intervention for Acute ST Elevated Myocardial Infarction in Assiut University	N/A
Completed	`NCT03156699` - The Incidence, Effect and Persistence of Fragmented-QRS, in Patients Presenting With ST-Elevation Myocardial Infarction
Enrolling by invitation	`NCT04970238` - Effect of Levosimendan on Left Ventricular Systolic Function and Heart Failure After PCI in Patients With Acute Anterior Myocardial Infarction	Phase 4
Recruiting	`NCT02557217` - NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction	Phase 2
Recruiting	`NCT02224534` - Ticagrelor Versus Clopidogrel in Left Ventricular Remodeling After ST-segment Elevation Myocardial Infarction	Phase 4
Completed	`NCT01136187` - Trial Comparing Radial and Femoral Approach in Primary Percutaneous Coronary Intervention (PCI)	N/A
Not yet recruiting	`NCT04068116` - Impact of Ischemic Post-conditioning	N/A
Not yet recruiting	`NCT04063345` - Long-term Clinical Outcomes of intraVascular Ultrasound-guided vs Angiography-guided Primary pErcutaneous Intervention in Patients With Acute ST Segment Elevated Myocardial Infarction	Phase 2/Phase 3
Active, not recruiting	`NCT03646357` - BEtablocker Treatment After Acute Myocardial Infarction in Patients Without Reduced Left Ventricular Systolic Function	Phase 4
Completed	`NCT03740776` - The Eosinophils Percentage Predicts In-hospital Major Adverse Cardiac Events in STEMI Patients After PCI
Completed	`NCT03984071` - The Predictive Value of eGFR for Adverse Cardiovascular Events in Patients With STEMI