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Clinical Trial Summary

This is a single-arm, open-lable study to determine the safety, tolerability and preliminary efficacy of oncolytic virus injection (RT-01) combined with or without immune checkpoint inhibitors (Nivolumab) in the treatment of patients with advanced solid tumors.


Clinical Trial Description

To evaluate the safety, tolerability, efficacy, immunoreactivity, immunogenicity, pharmacokinetics and virus shedding of RT-01 injection given via Intravenous with or without Intratumoral administration combined with immune checkpoint inhibitors Nivolumab in the treatment of patients with advanced solid tumors. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05122572
Study type Interventional
Source Wuxi People's Hospital
Contact Peihua Lu, MD
Phone +86 13621500031
Email 13625653@qq.com
Status Recruiting
Phase Phase 1
Start date November 1, 2021
Completion date June 1, 2023

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