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Sleep Disorders clinical trials

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NCT ID: NCT00786357 Completed - Clinical trials for Shift-Work Sleep Disorder

Sleep Enhancement Training Study for Experienced Shiftworkers

SETS-exp
Start date: November 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if a modified version of the Sleep Enhancement Fatigue Reduction Training (SEFRT) system can improve sleep and health-related symptoms and quality of life in experienced shift-working nurses.

NCT ID: NCT00786266 Completed - Clinical trials for Shift-Work Sleep Disorder

Sleep Enhancement Training Study for Novice Shiftworkers

SETS-novice
Start date: November 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if a modified version of the Sleep Enhancement Fatigue Reduction Training (SEFRT) system can improve sleep and health-related symptoms and quality of life in shiftwork-naive new nurse graduates.

NCT ID: NCT00748098 Completed - Clinical trials for Restless Legs Syndrome

Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep Disturbance

Start date: October 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of GSK1838262 extended release tablets in the treatment of patients with Restless Legs Syndrome and associated sleep disturbance.

NCT ID: NCT00723580 Completed - Insomnia Clinical Trials

Actigraphic Analysis of Treatment Response

Start date: May 2008
Phase: N/A
Study type: Interventional

The study examines and illustrates the utility of utilizing actigraphic measurements to assess treatment response.

NCT ID: NCT00694447 Completed - Pain Clinical Trials

Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis

Start date: February 2007
Phase: N/A
Study type: Interventional

The hypotheses of this study are: In the older population with knee OA, - When acupoints are chosen for both sleep and pain, there are additive effects on sleep improvement and pain relief (i.e. no interaction). - Main effects of acupuncture on sleep improvement and pain relief are anticipated when acupoints are separately targeted for sleep and for pain, respectively.

NCT ID: NCT00691626 Completed - Clinical trials for Posttraumatic Stress Disorder

Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans

Start date: April 1, 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effectiveness of two talk therapies for OEF/OIF Veterans at the Michael J. Crescenz and the West Haven VA Medical Centers. Participants will randomly receive one of two individual treatments intended to improve the sleep disturbance and nightmares of returning Veterans.

NCT ID: NCT00691080 Completed - Sleep Problems Clinical Trials

Understanding Sleep Problems in Children With Autism Spectrum Disorder

REST
Start date: September 2007
Phase: Phase 2/Phase 3
Study type: Observational

The investigators will examine whether sleep problems in children with autism spectrum disorder (ASD) are related to alterations in the production of melatonin (MT), a hormone that plays an important role in regulating sleep-wake cycle. Children with ASD experience high rates of sleep disturbances that potentially contribute to problems with thinking and behavior. It is unclear if changes in MT production cause sleep problems in children with ASD. MT is frequently used to treat these sleep problems; however, it has not been well established whether MT is an effective treatment. Our hypotheses concerning MT is children with ASD and sleep problems will have a delayed sleep-wake cycle and/or decreased MT production. This study will compare children diagnosed with ASD to "healthy" control children with no ASD diagnosis. All subjects will be recruited from one of three sites: Baylor College of Medicine, Oregon Health & Science University and Columbia University. The investigators will use a standardized questionnaire to determine whether the child has sleep problems. The investigators will measure MT levels in saliva in ASD children with sleep problems and in a group of control children without sleep problems. Total 24-hour MT production will be determined from urine samples in these same two groups.

NCT ID: NCT00688142 Completed - Clinical trials for Shift Work Sleep Disorder

Sleepiness and Brain Function: The Effect of Armodafinil in Shift Work Sleep Disorder

Start date: February 2008
Phase: N/A
Study type: Observational

The investigators hypothesize that in patients with shift work sleep disorder, armodafinil will specifically increase brain activity in the frontal cortex parallel with improvements in deficits of fundamental mechanisms of attention.

NCT ID: NCT00671190 Completed - Sleep Disorder Clinical Trials

Safety and Efficacy of Ramelteon in Healthy Subjects

Start date: March 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the phase-advance in circadian rhythms in healthy adults subjects taking ramelteon, once daily (QD).

NCT ID: NCT00645944 Completed - Schizophrenia Clinical Trials

Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With Schizophrenia

Start date: April 2008
Phase: N/A
Study type: Interventional

The major goal of this project is to investigate established insomnia treatments in a schizophrenia population to see if the improved sleep leads to overall better quality of life. In addition, we hypothesize that the insomnia treatment may also lead to observed improvements in other symptoms associated with schizophrenia such as cognitive impairments, obesity, and negative symptoms.