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Clinical Trial Summary

The objective of this study is to determine whether oral NAC is effective at attenuating COVID-19 disease symptom severity and duration of symptoms.


Clinical Trial Description

STUDY DESIGN: Randomized double-blinded placebo-controlled trial ELIGIBILITY Inclusion criteria: - age 18 years and older - participants will need daily access to use of a smartphone for at least six weeks from time of enrollment - Positive COVID-19 test within 10 days of date of enrollment - not already hospitalized for treatment of COVID Exclusion criteria: - pregnant - already hospitalized for treatment of COVID PROTOCOL - 50:50 randomization: half of participants will take NAC, half will take placebo - Participants will take NAC/placebo following this outpatient protocol: - 2400 mg x 1 PO then - 1200 mg PO BID x 14 days - Participants will complete an online symptom-tracker for six weeks (daily for three weeks, weekly for three weeks) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05074121
Study type Interventional
Source Cambridge Health Alliance
Contact Melisa Lai-Becker, MD
Phone 617-394-7424
Email melaibecker@cha.harvard.edu
Status Not yet recruiting
Phase Phase 2
Start date March 31, 2024
Completion date February 1, 2025

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