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Rupture clinical trials

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NCT ID: NCT01110382 Terminated - Infection Clinical Trials

A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections

Start date: December 2010
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of doripenem compared with meropenem in children hospitalized with complicated intra-abdominal infections.

NCT ID: NCT01109303 Completed - Clinical trials for Ankle Syndesmosis Rupture

Static Implant Versus Dynamic Implant in the Surgical Treatment on Ankle Syndesmosis Rupture

Start date: October 2008
Phase: N/A
Study type: Interventional

Ankle fracture is frequent and its number is increasing. In Canada, surgical treatment of these lesions is advised and the options currently used all have in common a rigid fixation of the syndesmosis which results in residual stiffness and a high level of secondary surgery, mostly to remove the implant. The purpose of the study is to compare the treatment of ankle syndesmotic rupture by a dynamic fixation to a static fixation suggesting that the dynamic fixation method will improve the Olerud-Molander functional score of more than 15 points at the 3 months follow-up.

NCT ID: NCT01069588 Completed - Clinical trials for Rupture of Anterior Cruciate Ligament

Anterior Cruciate Ligament (ACL) Reconstruction- Bioabsorbable Screw

Start date: December 2009
Phase:
Study type: Observational

To evaluate the knee functionality, screw integrity, graft integrity, cartilage effect, and bony ingrowth in patients treated with the CALAXO screw and MILAGRO screw two years after ACL reconstruction.

NCT ID: NCT01063686 Withdrawn - Ultrasonography Clinical Trials

The Cervical Cap in the Diagnosis of Rupture of Membranes in the Second Trimester

Start date: n/a
Phase: N/A
Study type: Interventional

Early preterm premature rupture of membranes (PPROM) complicates 0.7% of pregnancies. When PPROM occurs before the 24th week,the risk of fetal and neonatal death is 70%. There is also a high risk of neonatal and maternal morbidity. When the diagnosis of PPROM is uncertain by physical examination, additional tests are needed. These tests have false positive and false negative rates. The gold standard for diagnosing PPROM is amniocentesis and dye test. This procedure has a risk of infection and abortion.Our hypothesis is that by using a cervical cap for 6 hours and repeated ultrasound exams we can diagnose or rule out PPROM in cases which are uncertain. Our study group will be pregnant women gestational age 14-23, suspected of having PPROM.

NCT ID: NCT01050647 Completed - Clinical trials for Pregnancy Complications

Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.

Start date: February 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Preterm birth is the leading cause of neonatal death and a significant cause of life long disability and health problems. It has been shown that the drug 17-hydroxyprogesterone caproate can help reduce the risk of preterm delivery in women with certain risk factors for preterm birth. We hope to learn whether this same medication can be used to prolong pregnancy in a group of patients in whom this medication has not been previously studied. Specifically, we hope to learn whether progesterone supplementation will delay delivery in women with pre-term, premature rupture of membranes (PPROM).

NCT ID: NCT00975845 Completed - Clinical trials for Anterior Cruciate Ligament Rupture

BioCleanse Tibialis Tendon Anterior Cruciate Ligament (ACL) Study

Start date: November 9, 2017
Phase:
Study type: Observational

To compare the outcome of Anterior Cruciate Ligament (ACL) reconstruction performed using the tibialis allograft to historical outcomes of ACL reconstruction patients and to establish if any correlation exists between the age of the graft donor and the clinical outcomes.

NCT ID: NCT00940043 Completed - Clinical trials for Premature Rupture of Fetal Membranes

Monitoring of the Inflammatory Response of Patients With Premature Rupture of Membranes With Bedside Tests

EFFARM
Start date: September 2008
Phase: N/A
Study type: Observational

Prematurity represents 8% of birth and it is one of the leading causes of infant complications. The preterm premature rupture of membranes (PPROM) represents one-third of preterm birth and the rupture of membranes increase the risk of fetal exposition to infection which could lead to neurological sequels. Classic management of women with PPROM before 32SA is based on the extension of the pregnancy with the risk of adding complications like a secondary infection. Moreover, different studies have shown that fetal infection could be one of the most important risk factor for subsequent neurological complications. However, it is difficult to know if it is better to extend the pregnancy to gain in maturity or to arrest the pregnancy to avoid the risk of intrauterine infection. The research objective is to suggest a new strategy to manage women with PPROM. With this new strategy, the investigators seek to extend pregnancy as much as possible but the investigators would like to give birth before the intrauterine infection. The investigators suggest detecting protein associate with neurological complications of preterm child in the amniotic liquid found in the vagina of the mother. A positive test will lead to the delivery of the newborn before its infection. The hypothesis is that it is possible to study changes in the inflammatory status of patients who presented an PPROM from repeated detection of interleukins in vaginal secretions.

NCT ID: NCT00890630 Terminated - Clinical trials for Fetal Membranes, Premature Rupture

Intracervical Catheters for Induction of Labour in Women With Prelabour Rupture of Membranes at Term

IC-PROM
Start date: April 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to examine the feasibility of using intracervical balloon catheters for cervical ripening as part of labour induction in healthy, GBS-negative women with prelabour rupture of membranes at term.

NCT ID: NCT00837070 Completed - Clinical trials for Zygapophyseal Synovial Joint Cyst

Percutaneous Rupture of Zygapophyseal Joint Cysts

Start date: January 2009
Phase: Phase 2
Study type: Interventional

Lumbar zygapophyseal joint cysts can cause lower extremity radiculopathy. These cysts can be cured by a minimally invasive technique: percutaneous cyst distention and rupture

NCT ID: NCT00803153 Withdrawn - Clinical trials for Choroidal Detachment

PASCAL: Safety and Complications, Experience After 1301 Consecutive Cases

Start date: December 2008
Phase:
Study type: Observational

To report the safety and incidence of adverse effects, during and after a successful photocoagulation for different pathologies using a Pattern Scan Laser (PASCAL) system and its modified settings