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Rotator Cuff Tear clinical trials

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NCT ID: NCT01238302 Completed - Rotator Cuff Tear Clinical Trials

Arthroscopic Rotator Cuff Repair With Platelet-Rich Plasma(PRP) in Large to Massive Tears

Start date: July 2009
Phase: N/A
Study type: Interventional

- The purpose of this study is to compare the clinical and anatomical outcomes of rotator cuff repair with Platelet-Rich Plasma(PRP) and conventional rotator cuff repair in treatment of large to massive rotator cuff tears. - PRP application to arthroscopic rotator cuff repair would accelerate recovery after arthroscopic rotator cuff repair in terms of pain relief, functional outcomes, overall satisfaction, and enhance structural integrity of repaired tendon.

NCT ID: NCT01204606 Completed - Rotator Cuff Tear Clinical Trials

Arthroscopic Rotator Cuff Repair With Multimodal Analgesia(MMA)

Start date: September 2010
Phase: N/A
Study type: Interventional

- The purpose of this study is to compare the efficacy of periarticular injections consisting of ropivacaine, morphine, epinephrine, cefotetan, and hyaluronic acid with the efficacy of periarticular injections consisting of the same amount of placebo(isotonic saline) during arthroscopic rotator cuff repair. - Adding of multimodal analgesia(MMA) to conventional rotator cuff repair, it was expected that could reduce postoperative pain and narcotic consumption.

NCT ID: NCT01170312 Completed - Rotator Cuff Tear Clinical Trials

Arthroscopic Surgery and Platelet Rich Plasma In Rotator Cuff Tear Evaluation

ASPIRE
Start date: September 2010
Phase: N/A
Study type: Interventional

Rotator cuff tears are a common injury that lead to pain and loss of function for those who suffer from it. Treatment includes the use of arthroscopic surgery to return function to the patient and reduce their pain. This study is interested in a technique that has the potential to improve patient outcomes in terms of less pain and better function after their surgery. Autologous Conditioned Plasma (ACP) or Platelet Rich Plasma (PRP) is the intervention of interest, which is simply the patient's own blood that is withdrawn and spun down to obtain a high concentration of cells called platelets. Platelets release growth factors important for healing, as well as fibrin, which acts like a biological glue. The PRP is then re-injected into the shoulder at the time of surgery and again at 4 weeks. It has been shown to accelerate healing in other studies for injuries such as chronic elbow tendinopathy, but there is no randomized controlled trial that evaluates the effect of PRP in rotator cuff tears. It is on this basis that the study is being performed. Participating patients will receive either a PRP injection or a placebo (normal saline) and the effects will be compared at 2 weeks, 4 weeks, and 6 weeks based on a pain score and return to function questionnaires. The primary hypothesis for this study is that ACP compared with placebo is effective in reducing pain at the site of a rotator cuff injury that has undergone arthroscopic repair. It is expected that ACP administered during surgery and 4 weeks post-surgery will reduce 6-week pain scores compared to the placebo group.

NCT ID: NCT01140230 Completed - Rotator Cuff Tear Clinical Trials

Outcomes After Repair of Acute Rotator Cuff Tears

HBStud2
Start date: August 2009
Phase: N/A
Study type: Observational

Few studies are considering acute traumatic rotator cuff tears in previously asymptomatic patients. The purpose of the current study was to investigate if delay of surgery, age at repair and the number of cuff tendons involved affected the structural and clinical outcomes.

NCT ID: NCT01126593 Completed - Rotator Cuff Tear Clinical Trials

Post-Op Rotator Cuff Pain Study With Subacromial Bupivacaine Infusion

Start date: December 2008
Phase: N/A
Study type: Interventional

Subacromial pain catheters have been used with uncertain efficacy for many years after rotator cuff repair to aid in postoperative pain control. Our null hypothesis is that postoperative subacromial continuous infusion bupivacaine catheters will provide no pain control benefits over placebo infusions or no catheter use.

NCT ID: NCT01086202 Completed - Rotator Cuff Tear Clinical Trials

Clinical Outcome Comparison Between Medial and Lateral Offset Reverse Shoulder Arthroplasty

Start date: May 2010
Phase: N/A
Study type: Observational

The purpose of this study is to prospectively evaluate two FDA approved implant designs for the Tornier Reverse Shoulder arthroplasty. The small difference in design is the amount of offset each implant has. This offset may improve clinical outcomes in the patient population. There have been no clinical comparative studies between these two designs in the literature to date. We would like to follow these patients for two years after implantation of the reverse shoulder and evaluate their radiographs, pain scores, and shoulder functional scores. this would be the first randomized prospective single blinded study of its kind.

NCT ID: NCT01085942 Completed - Rotator Cuff Tear Clinical Trials

Longitudinal Study of Asymptomatic Rotator Cuff Tears

Start date: October 2008
Phase: N/A
Study type: Observational

The purpose of this study is to analyze the natural course of asymptomatic rotator cuff tears.

NCT ID: NCT01039571 Completed - Rotator Cuff Tear Clinical Trials

Single Versus Double Row Suture Anchor Repair in Medium to Large Rotator Cuff Tears

Start date: January 2005
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether double row repair is better in healing than traditional single row repair in arthroscopic rotator cuff repair. Our null hypothesis is there are no differences in clinical and structural results

NCT ID: NCT01025037 Completed - Rotator Cuff Tear Clinical Trials

Outcomes in Rotator Cuff Repair Using Graft Reinforcement

Start date: October 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate patient shoulder functional outcomes following rotator cuff repairs reinforced with a surgical mesh.

NCT ID: NCT00923858 Completed - Rotator Cuff Tear Clinical Trials

The Natural History of Asymptomatic Rotator Cuff Tears

Start date: July 1, 2005
Phase:
Study type: Observational

The purpose of this project is to provide information which can help us understand what happens over time to rotator cuff tears. In this study, the investigators will follow a population of people with rotator cuff tears that do not hurt (asymptomatic) and to establish the probability that an asymptomatic rotator cuff tear, identified in the context of contralateral symptoms, will become symptomatic over time. To determine with ultrasound the probability that a rotator cuff tear will enlarge over time. To determine if symptom progression correlates with enlargement of the rotator cuff tear and/or degenerative changes on radiographs. In order to obtain data, study subjects will be recalled for follow-up at 1 year time points over a 5 year period. The study subjects will have repeat physical exam, ultrasound and radiographic examinations. A control group of normal patients will also be followed for comparison.