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Rheumatoid Arthritis Memory B Cells and Abatacept — RAMBA  

Rheumatoid Arthritis Clinical Trial

Official title:
Rheumatoid Arthritis Memory B Cells and Abatacept (RAMBA)

Clinical Trial Summary

Single-Open Label Study to Assess Changes in the Immune Profile in Response to Treatment with Intravenous Abatacept Adults with Rheumatoid Arthritis who are Naive to Biologic Disease-Modifying Antirheumatic Drugs

Clinical Trial Description

The immune system of patients with Rheumatoid Arthritis (RA) is different from that of people who do not have RA. The purpose of this study is to examine participants' immune cells and proteins before initiation of study medication and after initiation of treatment with an approved therapy for RA, abatacept that will be given in combination with Methotrexate and/or anti-rheumatic drugs (DMARDS) that are approved for the treatment of RA. This study will assess whether participants have clinically responded to these medications. This assessment will also include a study of whether characteristics of participants' immune systems were changed by therapy with the study drug, abatacept. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03652961
Study type Interventional
Source NYU Langone Health
Contact
Status Active, not recruiting
Phase Phase 4
Start date June 2, 2019
Completion date May 30, 2024
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