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Dose Reduction for Early Rheumatoid Arthritis Patients With Low Disease Activity

Rheumatoid Arthritis Clinical Trial

Official title:
A Multicenter, Randomized, Open-label, Blinded-assessor, Follow-up, Phase 4 Study in Patients With Rheumatoid Arthritis Who Have Completed the Initial Treatment Part in the NORD-STAR Study and Have Reached Stable Low Disease Activity

Clinical Trial Summary

This is an international (Nordic) trial designed to compare the safety and efficacy of active conventional therapy (ACT) and three biologic treatments (Certolizumab-pegol, Abatacept or Tocilizumab) in subjects with early rheumatoid arthritis (RA). The global aim of this study is to assess and compare two alternative de-escalation strategies in patients who achieved low disease activity during first-line therapy in the NORD-STAR study.

Clinical Trial Description

25 patients have been included in the study of which 1 has had an early termination an 22 have completed the full study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02466581
Study type Interventional
Source Karolinska Institutet
Contact
Status Active, not recruiting
Phase Phase 4
Start date February 3, 2015
Completion date December 2023
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