Meditation-Based Stress Reduction in Rheumatoid Arthritis

Rheumatoid Arthritis Clinical Trial

Official title:

Mindfulness Meditation-Based Stress Reduction in Relieving Symptoms Associated With Rheumatoid Arthritis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00071292
• Other study ID #: P50AT000084
• Secondary ID: Pradhan, Elizabe
• Status: Completed
• Phase: Phase 2
• First received: October 17, 2003
• Last updated: March 5, 2008
• Start date: July 2003
• Est. completion date: March 2005

Study information

• Verified date: March 2008
• Source: National Center for Complementary and Integrative Health (NCCIH)
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Federal Government
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine whether a mindfulness meditation-based stress reduction program is useful in relieving symptoms associated with rheumatoid arthritis (RA).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: March 2005
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion criteria:

• Confirmed diagnosis of RA, with doctor's letter or doctors' bill with ICD code 714;

• 18 years of age or older;

• Able to read and write English;

• Able to attend 15 course sessions and questionnaire sessions at Kernan Hospital in Baltimore;

• Willing to practice skills for 45 minutes to 1 hour per day, 6 days a week;

• Stable on rheumatoid medications for at least one month.

Exclusion criteria:

• Major psychiatric illness (bipolar disorder, multiple personality disorder, etc.);

• Active alcoholism or drug dependency;

• Scheduled for major surgery during the study period;

• Enrolled in randomized clinical trial for rheumatoid arthritis during the study period;

• Planning to move out of the area in the next 12 months;

• Unwilling to be enrolled in a control group;

• Use of assistive device other than a cane;

• Serious health condition(s) that the investigator determines would make it difficult to complete the 6 month study;

• Diagnosis of fibromyalgia.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Arthritis
• Arthritis, Rheumatoid
• Rheumatoid Arthritis

Intervention

Behavioral:
• stress reduction program

• meditation

Locations

Country	Name	City	State
United States	University of Maryland School of Medicine - Kernan Hospital	Baltimore	Maryland

Sponsors (1)

Lead Sponsor	Collaborator
National Center for Complementary and Integrative Health (NCCIH)

Country where clinical trial is conducted

United States, 

References & Publications (5)

Kabat-Zinn J, Lipworth L, Burney R. The clinical use of mindfulness meditation for the self-regulation of chronic pain. J Behav Med. 1985 Jun;8(2):163-90. — View Citation

Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF. Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. Am J Psychiatry. 1992 Jul;149(7):936-43. — View Citation

Kabat-Zinn J. An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results. Gen Hosp Psychiatry. 1982 Apr;4(1):33-47. — View Citation

Kaplan KH, Goldenberg DL, Galvin-Nadeau M. The impact of a meditation-based stress reduction program on fibromyalgia. Gen Hosp Psychiatry. 1993 Sep;15(5):284-9. — View Citation

Miller JJ, Fletcher K, Kabat-Zinn J. Three-year follow-up and clinical implications of a mindfulness meditation-based stress reduction intervention in the treatment of anxiety disorders. Gen Hosp Psychiatry. 1995 May;17(3):192-200. — View Citation

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