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Retinal Detachment clinical trials

View clinical trials related to Retinal Detachment.

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NCT ID: NCT02896972 Completed - Clinical trials for Macular Hole Retinal Detachment

Inverted Internal Limiting Membrane Flap Technique for Macular Hole Retinal Detachment in Highly Myopic Eyes

Start date: April 2012
Phase: N/A
Study type: Interventional

To evaluate efficacy of vitrectomy with inverted internal limiting membrane (ILM) flap technique for macular hole retinal detachment (MHRD) in highly myopic eyes, and to demonstrate postoperative clinical course of MHRD after inverted ILM flap technique using swept-source optical coherence tomography (OCT)

NCT ID: NCT02841306 Completed - Clinical trials for Rhegmatogenous Retinal Detachment

Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment

UDCA-RD
Start date: July 2016
Phase: Phase 1
Study type: Interventional

26 patients presenting a rhegmatogenous retinal detachment with more than 4 days of duration will be prospectively included. A single dose of ursodeoxycholic acid will be administered orally before surgery at different time-points in 22 subjects. Standard surgery will be performed and ocular samples will be collected during the procedure. Ursodeoxycholic acid treatment will be continued in treated patients during 3 months after surgery. Ocular and serum samples from the 4 untreated patients will serve as negative controls for the determination of UDCA levels.

NCT ID: NCT02834559 Completed - Clinical trials for Rhegmatogenous Retinal Detachment

Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment.

PRIVENT
Start date: October 27, 2016
Phase: Phase 3
Study type: Interventional

This study investigates the effectiveness of a simple treatment to prevent proliferative vitreoretinopathy (PVR). Intraoperative intravitreal 5-fluorouracil (5-FU) and low molecular weight heparin (LMWH) is used as a prophylactic therapy in high-risk patients with primary rhegmatogenous retinal detachment (RRD). Our major motivation is to reduce the incidence of PVR in the group that receives the trial drug.

NCT ID: NCT02816710 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy

Start date: July 2016
Phase: Phase 4
Study type: Interventional

To evaluate efficacy of different intravitreal Conbercept injection therapy in the treatment of severe proliferative diabetic retinopathy.

NCT ID: NCT02748538 Completed - Retinal Detachment Clinical Trials

The Posturing After Retinal Detachment (Post RD) Trial

Start date: May 17, 2016
Phase:
Study type: Observational

A randomised controlled trial to evaluate the effect of face-down posturing on retinal displacement and distortion following retinal detachment repair.

NCT ID: NCT02715388 Completed - Retinal Detachment Clinical Trials

Proof of Concept - Digital Electro-optical Surgical Platform as Replacement for Operational Microscopes

Start date: January 2016
Phase: N/A
Study type: Interventional

Evaluate the use of Elbit's digital electro-optical systems for generating detailed high quality video imaging during surgery, and thus improving the surgeon's visualization, performance and outcome.

NCT ID: NCT02682797 Completed - Retinoschisis Clinical Trials

Optical Coherence Tomography Evaluation of Retinoschisis and Retinal Detachment

Start date: September 2013
Phase: N/A
Study type: Observational

Retinoschisis is usually a rare self-limited disease and seldom shows progression. There a splitting of the neurosensory retina occurs usually in the inferior temporal. Patients usually have good visual acuity and are asymptomatic. Combination of an inner and outer layer hole is considered high risk factor for development of a schisis detachment. The most important differential diagnosis is an retinal detachment, since if misdiagnosed unnecessary treatment is provided. In clinical examination, both can appear very thin and transparent. Therefore exact diagnosis of retinoschisis and retinal detachment has to be assessed and regular follow-up controls have to be conducted for sufficient recognition of progression.

NCT ID: NCT02528045 Completed - Clinical trials for Myopic Traction Maculopathy

Vitrectomy and Scleral Shortening for Macular Hole Retinal Detachment or Myopic Traction Maculopathy

Start date: June 2012
Phase: N/A
Study type: Observational

The medical records of 16 eyes of 16 patients with macular hole retinal detachment or myopic traction maculopathy who received viterctomy including internal limiting membrane peeling and scleral shorting surgery were reviewed. Best-corrected visual acuity, axial length, retinal reattachment and macular hole closure, the shape of staphyloma determined by optical coherence tomography and 3-dimensional magnetic resonance imaging were assessed.

NCT ID: NCT02423382 Completed - Retinal Detachment Clinical Trials

Measurement of the Retinal Oxygen Saturaiton After Long-term Silicon Oil Tamponade

Start date: February 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effects of long-term tamponade with silicone oil on retinal saturation with Oxymap.

NCT ID: NCT02423161 Completed - Retinal Detachment Clinical Trials

PIONEER: Intraoperative and Perioperative OCT Study

PIONEER
Start date: August 2011
Phase: N/A
Study type: Observational

OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician. Utilizing this information during surgery will allow for ophthalmic surgeons to better understand how surgical procedures impact the anatomic structure of the eye.